揭示可用药基因组的曙光。
Glimmers in illuminating the druggable genome.
机构信息
Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Office of the Director, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland 20817, USA.
出版信息
Nat Rev Drug Discov. 2018 May;17(5):301-302. doi: 10.1038/nrd.2017.252. Epub 2018 Jan 19.
Abstract
Much biomedical research continues to focus on a small proportion of the human genome that has already been studied intensively. The Illuminating the Druggable Genome programme, initiated as a pilot project by the US National Institutes of Health Common Fund in 2014, is now being implemented to accelerate the investigation of subsets of understudied proteins that have potential therapeutic relevance.
摘要
许多生物医学研究仍然集中在已经被深入研究过的一小部分人类基因组上。Illuminating the Druggable Genome 计划于 2014 年由美国国立卫生研究院共同基金作为试点项目发起，目前正在实施，以加速对具有潜在治疗相关性的研究较少的蛋白质亚类的研究。
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