Seck M C, Ndiaye D, Diongue K, Ndiaye M, Badiane A S, Sow D, Sylla K, Tine R, Ndiaye J L, Faye B, Ndir O
Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontostomatologie, université Cheikh Anta Diop, BP5005, Dakar, Sénégal; Laboratoire de parasitologie-mycologie, CHU Aristide le Dantec, BP16477, Dakar, Sénégal.
Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontostomatologie, université Cheikh Anta Diop, BP5005, Dakar, Sénégal; Laboratoire de parasitologie-mycologie, CHU Aristide le Dantec, BP16477, Dakar, Sénégal.
J Mycol Med. 2014 Jun;24(2):124-8. doi: 10.1016/j.mycmed.2014.02.002. Epub 2014 Mar 14.
Onychomycosis are a mycose of nail due to fungi. According to published data, they stands for half of all nail abnormalities. This survey was carried out to determine the frequency and the fungi involved in onychomycosis in Dakar.
This study was carried out at the laboratory of parasitology and mycology at Le Dantec Hospital, in Senegal from January 2008 to December 2012 and includes 507 patients.
Onychomycosis were mycologically proved in 58.78% (298/507) of patients. Patient's age varies between 02 years to 82 years with a mean of 34.24 years. Women were more infected than men (sex-ratio was 2.38). Onychomycosis due to dermatophyte represented 37.92% (113/298) of patients and were essentially located on toes (60.71%). Distal and lateral subungual onychomycosis was the most frequent clinical form. Trichophyton rubrum and Trichophyton interdigitale were isolated respectively in 53.6% and 26.1% on toes. Yeasts represented 59.06% (176/298) of onychomycosis and were essentially located on fingernails (80.11%). Candida albicans represented 90.86% of isolated yeasts. Molds were isolated in nine cases (3.02%) and predominated in toenails.
Among 507 patients with onychopathy, this study identified 298 cases of onychomycosis. T. rubrum was the main dermatophytes and was isolated on toenails whereas on fingernails C. albicans was more often observed.
甲真菌病是由真菌引起的指甲霉菌感染。根据已发表的数据，它们占所有指甲异常的一半。本次调查旨在确定达喀尔甲真菌病的发病率以及所涉及的真菌种类。
本研究于2008年1月至2012年12月在塞内加尔勒丹泰克医院的寄生虫学和真菌学实验室进行，共纳入507例患者。
58.78%（298/507）的患者经真菌学证实患有甲真菌病。患者年龄在2岁至82岁之间，平均年龄为34.24岁。女性感染率高于男性（性别比为2.38）。皮肤癣菌引起的甲真菌病占患者的37.92%（113/298），主要发生在脚趾（60.71%）。远端和侧位甲下甲真菌病是最常见的临床类型。红色毛癣菌和指间毛癣菌分别在53.6%和26.1%的脚趾上分离出来。酵母菌占甲真菌病的59.06%（176/298），主要发生在手指甲（80.11%）。白色念珠菌占分离出酵母菌的90.86%。霉菌在9例（3.02%）中分离出来，主要发生在脚趾甲。
在507例甲病患者中，本研究确定了298例甲真菌病。红色毛癣菌是主要的皮肤癣菌，在脚趾甲上分离出来，而在手指甲上更常观察到白色念珠菌。
