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1
Synthesis and Structure-Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia.
ACS Med Chem Lett. 2017 Dec 14;9(1):61-64. doi: 10.1021/acsmedchemlett.7b00479. eCollection 2018 Jan 11.
2
The synthetic toxin biliatresone causes biliary atresia in mice.
Lab Invest. 2020 Nov;100(11):1425-1435. doi: 10.1038/s41374-020-0467-7. Epub 2020 Jul 17.
3
Identification of a plant isoflavonoid that causes biliary atresia.
Sci Transl Med. 2015 May 6;7(286):286ra67. doi: 10.1126/scitranslmed.aaa1652.
4
Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids.
Chem Res Toxicol. 2016 Feb 15;29(2):142-9. doi: 10.1021/acs.chemrestox.5b00308. Epub 2016 Jan 13.
6
Biliatresone induces cholangiopathy in C57BL/6J neonates.
Sci Rep. 2023 Jun 29;13(1):10574. doi: 10.1038/s41598-023-37354-z.
7
Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone.
Chem Res Toxicol. 2015 Aug 17;28(8):1519-21. doi: 10.1021/acs.chemrestox.5b00227. Epub 2015 Jul 20.
8
Biliary tract: Newly identified biliatresone causes biliary atresia.
Nat Rev Gastroenterol Hepatol. 2015 Jul;12(7):369. doi: 10.1038/nrgastro.2015.91. Epub 2015 May 26.
9
Biliary Atresia: Clinical and Research Challenges for the Twenty-First Century.
Hepatology. 2018 Sep;68(3):1163-1173. doi: 10.1002/hep.29905.
10
A single-repeat MYB transcription factor, GmMYB176, regulates CHS8 gene expression and affects isoflavonoid biosynthesis in soybean.
Plant J. 2010 Jun 1;62(6):1019-34. doi: 10.1111/j.1365-313X.2010.04214.x. Epub 2010 Mar 25.

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1
Microcystin-RR is a biliary toxin selective for neonatal extrahepatic cholangiocytes.
JHEP Rep. 2024 Sep 12;7(1):101218. doi: 10.1016/j.jhepr.2024.101218. eCollection 2025 Jan.
2
Biliary atresia.
Nat Rev Dis Primers. 2024 Jul 11;10(1):47. doi: 10.1038/s41572-024-00533-x.
6
Biliatresone: progress in biliary atresia study.
World J Pediatr. 2023 May;19(5):417-424. doi: 10.1007/s12519-022-00619-0. Epub 2022 Sep 27.
7
Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia.
Gastroenterology. 2020 Sep;159(3):1068-1084.e2. doi: 10.1053/j.gastro.2020.05.080. Epub 2020 Jun 4.

本文引用的文献

1
Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone.
Chem Res Toxicol. 2015 Aug 17;28(8):1519-21. doi: 10.1021/acs.chemrestox.5b00227. Epub 2015 Jul 20.
2
Identification of a plant isoflavonoid that causes biliary atresia.
Sci Transl Med. 2015 May 6;7(286):286ra67. doi: 10.1126/scitranslmed.aaa1652.
4
Extrahepatic cholangiocyte cilia are abnormal in biliary atresia.
J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):96-101. doi: 10.1097/MPG.0b013e318296e525.
7
Biliary atresia.
Gastroenterol Clin North Am. 2003 Sep;32(3):891-911. doi: 10.1016/s0889-8553(03)00049-9.
8
Palladium-catalyzed alpha-arylation of carbonyl compounds and nitriles.
Acc Chem Res. 2003 Apr;36(4):234-45. doi: 10.1021/ar0201106.

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