Greenberg S Bruce, Lang Sean M, Gauss C Heath, Lensing Shelly Y, Ali Sumera, Lyons Karen A
Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Slot #105, 1 Children's Way, Little Rock, AR, 72202, USA.
Children's Hospital of Boston, Boston, MA, USA.
Int J Cardiovasc Imaging. 2018 Jun;34(6):967-974. doi: 10.1007/s10554-018-1303-7. Epub 2018 Jan 18.
To establish standards for pulmonary artery and branch pulmonary artery (PA and BPA) effective diameter (ED) and cross-sectional area (CSA) by using computed tomography (CT) data in children of a wide range of sizes and investigate the roundness of arteries. The ED (average of short and long axes) and CSA for the PA and BPA were measured using 1-mm collimation double-oblique reconstructions. Ordinary least squares regression was used to investigate models with various functional forms that related ED and CSA to patient size. Aspect ratio (AR), the short axis divided by long axis, was measured to evaluate roundness. The ideal diameter derived from CSA measurements was compared to ED, short axis, and long axis measurements. 108 CT examinations were analyzed in children without reason for abnormal PA size who ranged in age from 0 to 18 years (mean, 10.9 years; SD, 5.9 years). Interrater reliability was excellent. Data were modeled using a natural log-transformed response variable and a linear term for height as the independent variable. AR for the PA, right pulmonary artery, and left pulmonary artery measured < 0.9 for 38, 55, and 37%, respectively, indicating that many arteries are not round. Ideal diameter was not significantly different than ED but was for short- and long-axis diameter measurements. Normal ED and CSA for PA and BPA were determined for children of different sizes. Measurements outside of the normal range are consistent with dilatation or stenosis. Single diameter techniques are likely to introduce error.
利用计算机断层扫描（CT）数据为不同年龄段儿童建立肺动脉及分支肺动脉（PA和BPA）有效直径（ED）和横截面积（CSA）的标准，并研究动脉的圆度。使用1毫米准直双斜重建测量PA和BPA的ED（短轴和长轴的平均值）和CSA。采用普通最小二乘法回归研究将ED和CSA与患者体型相关联的各种函数形式的模型。测量纵横比（AR，短轴除以长轴）以评估圆度。将CSA测量得出的理想直径与ED、短轴和长轴测量值进行比较。对108例年龄在0至18岁（平均10.9岁；标准差5.9岁）、PA大小无异常原因的儿童进行了CT检查分析。评分者间信度极佳。使用自然对数变换的响应变量和身高的线性项作为自变量对数据进行建模。PA、右肺动脉和左肺动脉的AR分别有38%、55%和37%测量值<0.9，表明许多动脉并非圆形。理想直径与ED无显著差异，但与短轴和长轴直径测量值有差异。确定了不同体型儿童PA和BPA的正常ED和CSA。超出正常范围的测量结果与扩张或狭窄一致。单直径技术可能会引入误差。
