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社会经济因素对波兰老年人群维生素 D 缺乏的影响:来自 PolSenior 研究的结果。

Socio-economic determinants of vitamin D deficiency in the older Polish population: results from the PolSenior study.

机构信息

1Pathophysiology Unit,Department of Pathophysiology,Medical School in Katowice,Medical University of Silesia,Medyków Street 18,40-752 Katowice,Poland.

2Department of Statistics,Department of Instrumental Analysis,School of Pharmacy and Laboratory Medicine in Sosnowiec,Medical University of Silesia,Katowice,Poland.

出版信息

Public Health Nutr. 2018 Aug;21(11):1995-2003. doi: 10.1017/S1368980017003901. Epub 2018 Jan 21.

Abstract

OBJECTIVE

Numerous studies have reported an association between vitamin D (25-hydroxyvitamin D; 25(OH)D) deficiency and low economic status, lower educational level, drugs exposure, smoking and reduced physical activity. Our study analysed the association between sociodemographic factors and 25(OH)D status in Polish (Caucasian) seniors.

DESIGN

Cross-sectional study (part of the PolSenior study). Serum 25(OH)D concentration was measured by a solid-phase ELISA method; a standardized questionnaire evaluated educational level, economic status, alcohol consumption, current or past cigarette smoking, physical activity, activities of daily living (ADL) and instrumental activities of daily living.

SETTING

Community-dwelling randomly selected individuals aged 65 years or older, selected using three-stage stratified, proportional draw.

SUBJECTS

Seniors (n 3472; 1658 women and 1814 men).

RESULTS

Mean serum 25(OH)D concentration was 20·5 (sd 9·6) ng/ml. Values below the recommended level (30 ng/ml) were detected in 82·8 % of men and 90·4 % of women. Regression analysis revealed that the difference between sexes was associated with decreased walking activity in women, probably resulting in less sunlight exposure. There was a positive association between any disability in ADL and the presence of vitamin D deficiency/insufficiency. In the sex-adjusted analysis, older age, alcohol abstinence and lack of cycling and long-distance walking were explanatory variables for vitamin D deficiency.

CONCLUSIONS

Vitamin D deficiency/insufficiency is frequent in the older Polish population and associated with functional disability and impaired mobility of seniors.

摘要

目的

许多研究报告称,维生素 D(25-羟维生素 D;25(OH)D)缺乏与经济状况低、教育程度低、药物暴露、吸烟和体力活动减少有关。我们的研究分析了波兰(白种人)老年人社会人口因素与 25(OH)D 状态之间的关系。

设计

横断面研究(PolSenior 研究的一部分)。血清 25(OH)D 浓度通过固相 ELISA 法测定;标准化问卷评估了教育程度、经济状况、酒精摄入、当前或过去的吸烟情况、体力活动、日常生活活动(ADL)和工具性日常生活活动。

地点

社区居住的随机选择的 65 岁或以上的个体,使用三阶段分层、比例抽样法选择。

受试者

老年人(n 3472;1658 名女性和 1814 名男性)。

结果

平均血清 25(OH)D 浓度为 20.5(sd 9.6)ng/ml。82.8%的男性和 90.4%的女性检测值低于推荐水平(30ng/ml)。回归分析显示,性别差异与女性步行活动减少有关,可能导致阳光暴露减少。ADL 任何残疾与维生素 D 缺乏/不足呈正相关。在性别调整分析中,年龄较大、戒酒以及缺乏骑自行车和长途步行是维生素 D 缺乏的解释变量。

结论

波兰老年人群中维生素 D 缺乏/不足较为常见,与老年人的功能障碍和活动受限有关。

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