生活在阳光充足国家的老年社区男性的维生素 D 状况及其与生活方式因素的关联：澳大利亚悉尼的协和健康与老年男性项目。
Vitamin D status among older community dwelling men living in a sunny country and associations with lifestyle factors: the Concord Health and Ageing in Men Project, Sydney, Australia.
机构信息
Centre for Education and Research on Ageing, Concord Hospital, University of Sydney, NSW, Australia.
出版信息
J Nutr Health Aging. 2013 Jul;17(7):587-93. doi: 10.1007/s12603-013-0013-z.
OBJECTIVES
Inadequate vitamin D status (25-hydroxyvitamin D (25(OH)D) concentrations <50 nmol/L) is an increasingly important public health issue in Australia. The aim of this analysis is to describe 25(OH)D levels in community dwelling men aged ≥70 years in Sydney, Australia, and to determine associations between serum 25(OH)D levels and socioeconomic and lifestyle factors.
DESIGN
A population-based, cross-sectional analysis of the baseline phase of the Concord Health and Ageing in Men Project (CHAMP), a large epidemiological study conducted in Sydney between January 2005 and May 2007.
PARTICIPANTS
1659 non-institutionalised men aged ≥70 years.
METHODS
The cross-sectional analysis of the baseline phase of the Concord Health and Ageing in Men Project (CHAMP), a large epidemiological study conducted in Sydney between January 2005 and May 2007. Participants included 1659 community dwelling men who were interviewed and had clinical assessments. Main outcome measurements included serum 25(OH)D levels measured in blood samples using a radioimmunoassay kit (DiaSorin Inc., Stillwater, MN). Covariates included age, socioeconomic measures, season of blood sample, physical activity, sun exposure, vitamin D supplement use, cigarette smoking status, alcohol consumption, obesity and measures of health.
RESULTS
Prevalence of vitamin D insufficiency was 43.0%; highest in winter (55.5%) and spring (53.9%), and was associated with season (winter and spring), low physical activity, avoidance of sun exposure, current smoking and obesity, even after adjustment for confounding factors.
CONCLUSION
Inadequate vitamin D status is highly prevalent among Australian older men and is associated with specific lifestyle factors. These findings emphasize the need to screen and monitor 25(OH)D levels in this population group, despite living in a sunny country such as Australia.
目的
维生素 D 状态不足（25-羟维生素 D（25（OH）D）浓度<50nmol/L）在澳大利亚是一个日益重要的公共卫生问题。本分析的目的是描述澳大利亚悉尼社区居住的 70 岁以上男性的 25（OH）D 水平，并确定血清 25（OH）D 水平与社会经济和生活方式因素之间的关系。
设计
这是 2005 年 1 月至 2007 年 5 月在悉尼进行的一项大型流行病学研究——“康科德男性健康与衰老研究”（CHAMP）的基线阶段的一项基于人群的横断面分析。
参与者
1659 名非住院 70 岁以上男性。
方法
这是 2005 年 1 月至 2007 年 5 月在悉尼进行的一项大型流行病学研究——“康科德男性健康与衰老研究”（CHAMP）的基线阶段的一项基于人群的横断面分析。参与者包括 1659 名社区居住的男性，他们接受了访谈和临床评估。主要观察指标包括使用放射免疫试剂盒（DiaSorin Inc.，Stillwater，MN）测量血液样本中的血清 25（OH）D 水平。协变量包括年龄、社会经济指标、血液样本采集季节、体力活动、阳光暴露、维生素 D 补充剂使用、吸烟状况、饮酒量、肥胖以及健康状况。
结果
维生素 D 不足的患病率为 43.0%；冬季（55.5%）和春季（53.9%）最高，与季节（冬季和春季）、低体力活动、避免阳光暴露、当前吸烟和肥胖有关，即使在调整混杂因素后也是如此。
结论
澳大利亚老年男性维生素 D 状态不足的情况非常普遍，且与特定的生活方式因素有关。这些发现强调了即使在澳大利亚这样的阳光充足的国家，也需要对这一人群群体进行 25（OH）D 水平的筛查和监测。
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