Qi Xuezhi, Chen Lizhen, Zhang Xiaoning, Han Mingjuan, He Wei, Su Yangshuai, Wang Xiaoyu, Jing Xianghong, Zhu Bing
Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Zhongguo Zhen Jiu. 2017 Sep 12;37(9):963-6. doi: 10.13703/j.0255-2930.2017.09.014.
To judge whether algesia sensitization of some acupoints is existed and whether the acupoint algesia sensitization area is expanded in the patients of intestinal cancer.
Totally, 30 patients of intestinal cancer and 30 healthy subjects were included. The electronic Von Fray was used to determine the pressure-pain thresholds at 13 acupoints relevant with gastrointestinal disorders and the reference points at the sites 1 and 2 lateral to those points as well as the sites at the corresponding nerve segments. Compared with the pressure-pain thresholds at the reference points of the different segments, the relative value was calculated. The changes were analyzed in the pressure-pain thresholds at the relevant acupoints on the body surface in the patients of intestinal cancer as compared with the relative pressure-pain thresholds in the healthy volunteers.
The pressure-pain thresholds at Zusanli (ST 36), Shangjuxu (ST 37), Xiajuxu (ST 39), Quchi (LI 11) and Dachangshu (BL 25) in the patients of intestinal cancer were all significantly reduced as compared with those of the healthy subjects (<0.05, <0.01, <0.001). At the non-acupoint sites 1 and 2 lateral to those acupoints as well as at the sites of the same segments, the pressure-pain thresholds were reduced significantly as compared with the control group (<0.05, <0.01, <0.001). Particularly, the sensitization zone of Yinlingquan (SP 9) focused on the acupoint, the site 1 lateral to it as well as the non-acupoint sites of the same segments (<0.01, <0.001).
The acupoint sensitization is displayed at Zusanli (ST 36), Shangjuxu (ST 37), Xiajuxu (ST 39), Quchi (LI 11), Dachangshu (BL 25) and Yinlingquan (SP 9) and the sensitization area is expended in the patients of intestinal cancer.
判断结肠癌患者是否存在某些穴位的痛觉过敏以及穴位痛觉过敏区域是否扩大。
共纳入30例结肠癌患者和30名健康受试者。使用电子Von Fray测定与胃肠疾病相关的13个穴位及其旁开1寸、2寸部位以及相应神经节段部位的压痛阈值。与不同节段对照点的压痛阈值比较，计算相对值。分析结肠癌患者体表相关穴位压痛阈值与健康志愿者相对压痛阈值的变化情况。
结肠癌患者足三里（ST36）、上巨虚（ST37）、下巨虚（ST39）、曲池（LI11）和大肠俞（BL25）的压痛阈值均较健康受试者显著降低（<0.05，<0.01，<0.001）。在这些穴位旁开1寸、2寸的非穴位部位以及相同节段部位，压痛阈值较对照组显著降低（<0.05，<0.01，<0.001）。尤其阴陵泉（SP9）的敏化区集中在穴位本身、其旁开1寸部位以及相同节段的非穴位部位（<0.01，<0.001）。
结肠癌患者足三里（ST36）、上巨虚（ST37）、下巨虚（ST39）、曲池（LI11）、大肠俞（BL25）和阴陵泉（SP9）存在穴位敏化，且敏化区域扩大。
