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本文引用的文献

1
Laser Speckle Imaging of Sensitized Acupoints.致敏穴位的激光散斑成像
Evid Based Complement Alternat Med. 2018 Jul 17;2018:7308767. doi: 10.1155/2018/7308767. eCollection 2018.
2
[Subcutaneous Metabolites Involving Acupoint Sensitization Induced by Myocardial Ischemia and Acupuncture Stimulation in Rabbits].[家兔心肌缺血及针刺刺激诱导穴位敏化的皮下代谢产物]
Zhen Ci Yan Jiu. 2018 Jul 25;43(7):433-9. doi: 10.13702/j.1000-0607.180066.
3
Critical roles of TRPV2 channels, histamine H1 and adenosine A1 receptors in the initiation of acupoint signals for acupuncture analgesia.TRPV2 通道、组胺 H1 受体和腺苷 A1 受体在穴位信号启动中的关键作用,这些信号用于针刺镇痛。
Sci Rep. 2018 Apr 25;8(1):6523. doi: 10.1038/s41598-018-24654-y.
4
Comparison of the anti-apoptotic effects of 15- and 35-minute suspended moxibustion after focal cerebral ischemia/reperfusion injury.局灶性脑缺血/再灌注损伤后15分钟和35分钟悬灸抗凋亡作用的比较
Neural Regen Res. 2018 Feb;13(2):257-264. doi: 10.4103/1673-5374.226396.
5
Mast cells are important regulator of acupoint sensitization via the secretion of tryptase, 5-hydroxytryptamine, and histamine.肥大细胞通过分泌类胰蛋白酶、5-羟色胺和组胺,是穴位敏化的重要调节因子。
PLoS One. 2018 Mar 7;13(3):e0194022. doi: 10.1371/journal.pone.0194022. eCollection 2018.
6
Effects of dry needling trigger point therapy in the shoulder region on patients with upper extremity pain and dysfunction: a systematic review with meta-analysis.肩部触发点针刺疗法对上肢疼痛和功能障碍患者的影响:系统评价与荟萃分析。
Physiotherapy. 2018 Jun;104(2):167-177. doi: 10.1016/j.physio.2017.08.001. Epub 2017 Aug 7.
7
[Effects of heat-sensitive moxibustion on HPA axis in rats with irritable bowel syndrome].[热敏灸对肠易激综合征大鼠下丘脑-垂体-肾上腺轴的影响]
Zhongguo Zhen Jiu. 2017 Dec 12;37(12):1315-21. doi: 10.13703/j.0255-2930.2017.12.016.
8
[Distribution of algesia sensitized acupoints in the patients of intestinal cancer].[痛觉过敏致敏穴位在肠癌患者中的分布]
Zhongguo Zhen Jiu. 2017 Sep 12;37(9):963-6. doi: 10.13703/j.0255-2930.2017.09.014.
9
Appropriateness of sham or placebo acupuncture for randomized controlled trials of acupuncture for nonspecific low back pain: a systematic review and meta-analysis.假针刺或安慰剂针刺在非特异性腰痛针刺随机对照试验中的适用性:一项系统评价和荟萃分析。
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10
[Clinical Trials for Treatment of Allergic Rhinitis with Heat Sensitive Moxibustion and Its Regularity of Heat-sensitization Acupoint Distribution].[热敏灸治疗变应性鼻炎的临床试验及其热敏穴位分布规律]
Zhen Ci Yan Jiu. 2017 Dec 25;42(6):527-32. doi: 10.13702/j.1000-0607.2017.06.012.

理解穴位敏化:关于现象、潜在机制及临床应用的叙述性综述

Understanding Acupoint Sensitization: A Narrative Review on Phenomena, Potential Mechanism, and Clinical Application.

作者信息

Tan Huijuan, Tumilty Steve, Chapple Cathy, Liu Lizhou, McDonough Suzanne, Yin Haiyan, Yu Shuguang, Baxter G David

机构信息

Centre for Health, Activity and Rehabilitation Research, School of Physiotherapy, University of Otago, Dunedin, New Zealand.

Centre for Health and Rehabilitation Technologies, Institute of Nursing & Health Research, School of Health Sciences, Ulster University, Belfast, UK.

出版信息

Evid Based Complement Alternat Med. 2019 Aug 14;2019:6064358. doi: 10.1155/2019/6064358. eCollection 2019.

DOI:10.1155/2019/6064358
PMID:31485246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6710800/
Abstract

As part of traditional Chinese medicine, acupoints are considered a dynamic functional area, which can reflect the internal condition of the body. When the body is suffering from disease or injury, corresponding acupoints are believed to be activated and manifest in several sensitized forms, including expansion of the receptive field, pain sensitization, and heat sensitization. Such phenomena are believed to gradually disappear concomitantly with recovery from the disease. Acupoint states are therefore changeable according to health status, a phenomenon known as acupoint sensitization. This review aims to provide an overview of acupoint sensitization based on existing research results and determine priorities for future research. Systematic literature retrieval was conducted in Medline, Embase, Cochrane Library, CINAHL, and AMED from inception to 18 July 2018. Current evidence from research findings to date indicate that acupoint sensitization is based on neurogenic inflammation and that stimulation of sensitized acupoints presents a potential trend of generating a better clinical effect when compared with stimulation of unsensitized points.

摘要

作为中医的一部分,穴位被认为是一个动态的功能区域,能够反映身体的内部状况。当身体患有疾病或受到损伤时,相应的穴位被认为会被激活,并以几种敏感化形式表现出来,包括感受野扩大、疼痛敏感化和热敏感化。人们认为,随着疾病的康复,这些现象会逐渐消失。因此,穴位状态会根据健康状况而变化,这种现象被称为穴位敏化。本综述旨在基于现有研究结果对穴位敏化进行概述,并确定未来研究的重点。从创刊至2018年7月18日,在Medline、Embase、Cochrane图书馆、CINAHL和AMED中进行了系统的文献检索。迄今为止的研究结果表明,穴位敏化基于神经源性炎症,与未敏化穴位的刺激相比,刺激敏化穴位呈现出产生更好临床效果的潜在趋势。