Wang Shunji, Ye Gaxi, Zhang Yu, Guan Shuting, Liu Xiufen, Ren Wenjing
College of TCM, Ningxia Medical University, Yinchuan 750004, China.
Department of Acupuncture-Moxibustion, Ningxia Hui Autonomous Region Hospital of TCM, Yinchuan 750021.
Zhongguo Zhen Jiu. 2017 Oct 12;37(10):1047-51. doi: 10.13703/j.0255-2930.2017.10.006.
To compare the effects of flipping moxibustion of medicine combined with western medication and simple western medication for rheumatoid arthritis with cold dampness syndrome.
Eighty patients were randomly assigned into an observation group and a control group, 40 cases in each group. Oral methotrexate (1 time a week) and sulfasalazine (twice a day except the day for methotrexate) were used in the two groups. Patients in the observation group were treated with flipping moxibustion of medicine, twice a week. The main acupoints were Shenshu (BL 23), Guanyuan (CV 4), Zusanli (ST 36), Yinlingquan (SP 9), and the matching acupoints were in the meridians related to the disease location. All the treatment was given for continuous 4 weeks. The TCM symptom score, visual analogue scale (VAS) score, blood sedimentation (ESR), rheumatoid factor (RF) and C-reactive protein (CRP) were observed before and after treatment. The effect was evaluated.
The total effect rate in the observation group was 95.0% (38/40), which was better than 77.5% (31/40) in the control group (<0.05). After treatment, the VAS score, TCM symptom score, RF, ESR, CRP levels decreased in the two groups (all <0.05), with better effects in the observation group (all <0.05). The adverse reactions in the observation group were lower than those in the control group.
Flipping moxibustion of medicine combined with western medication for rheumatoid arthritis with cold dampness syndrome are better than simple western medication, which are safer and more effective.
比较药物翻转灸联合西药与单纯西药治疗寒湿痹阻型类风湿关节炎的疗效。
将80例患者随机分为观察组和对照组,每组40例。两组均口服甲氨蝶呤(每周1次)和柳氮磺胺吡啶(除服用甲氨蝶呤当天外,每日2次)。观察组患者加用药物翻转灸治疗,每周2次。主穴取肾俞(BL 23)、关元(CV 4)、足三里(ST 36)、阴陵泉(SP 9),配穴根据病变部位所属经络选取。所有治疗持续4周。观察治疗前后的中医症状评分、视觉模拟量表(VAS)评分、血沉(ESR)、类风湿因子(RF)及C反应蛋白(CRP),并评价疗效。
观察组总有效率为95.0%(38/40),优于对照组的77.5%(31/40)(P<0.05)。治疗后,两组VAS评分、中医症状评分、RF、ESR、CRP水平均降低(均P<0.05),且观察组改善更明显(均P<0.05)。观察组不良反应低于对照组。
药物翻转灸联合西药治疗寒湿痹阻型类风湿关节炎的疗效优于单纯西药,且更安全有效。