Wang Chao, Ding Wentao, Yu Yingmei, Zhang Bo, Xu Dong, Zhang Chendi
South Branch of Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 102600, China.
Zhongguo Zhen Jiu. 2017 Oct 12;37(10):1069-72. doi: 10.13703/j.0255-2930.2017.10.011.
To compare the clinical efficacy differences between acupuncture at distal acupoints and local acupoints on treatment of xerophthalmia.
A total of 40 patients of xerophthalmia were randomly divided into a distal group and a local group, 20 cases in each one. One patient in local group lost contact, and finally 20 cases in the distal group and 19 cases in the local group finished treatment. The patients in the distal group were treated with acupuncture at Guangming (GB 37) and Diwuhui (GB 42), while those in the local group were treated with acupuncture at Cuanzhu (BL 2), Tongziliao (GB 1) and Taiyang (EX-HN 5). Patients in both groups were treated once a day, five times per week, and totally 2-week treatment were given. The subjective symptom based on visual analogue scale (VAS), tear secretion, ocular surface disease index (OSDI) and breakup time (BUT) were evaluated before treatment, after two-week treatment (end of treatment) and two weeks after end of treatment (follow-up visit) in the two groups.
After treatment and follow-up visit, the VAS, tear secretion, OSDI and BUT were all improved (<0.05, <0.01), but the differences of VAS and OSDI between the two groups were not significant (both >0.05). At follow-up visit, the differences of tear secretion and BUT between the two groups were significant (both <0.05).
The acupuncture at distal acupoints could relieve xerophthalmia symptoms, improve quality of life, increase tear secretion and prolong BUT, which is superior to local acupoints in long term.
比较远端穴位针刺与局部穴位针刺治疗干眼症的临床疗效差异。
将40例干眼症患者随机分为远端组和局部组，每组20例。局部组有1例患者失访，最终远端组20例、局部组19例完成治疗。远端组患者针刺光明（GB 37）和地五会（GB 42），局部组患者针刺攒竹（BL 2）、瞳子髎（GB 1）和太阳（EX-HN 5）。两组患者均每日治疗1次，每周治疗5次，共治疗2周。在治疗前、治疗2周后（治疗结束时）及治疗结束后2周（随访），对两组患者基于视觉模拟评分法（VAS）的主观症状、泪液分泌、眼表疾病指数（OSDI）和泪膜破裂时间（BUT）进行评估。
治疗及随访后，两组患者的VAS、泪液分泌、OSDI及BUT均有改善（均P<0.05，P<0.01），但两组间VAS及OSDI差异无统计学意义（均P>0.05）。随访时，两组间泪液分泌及BUT差异有统计学意义（均P<0.05）。
远端穴位针刺可缓解干眼症症状，提高生活质量，增加泪液分泌，延长BUT，长期效果优于局部穴位针刺。
