1 School of Nursing, Vanderbilt University, Nashville, TN, USA.
2 School of Medicine, Vanderbilt University, Nashville, TN, USA.
Integr Cancer Ther. 2018 Sep;17(3):774-784. doi: 10.1177/1534735417753540. Epub 2018 Jan 22.
Treatment for head and neck cancer (HNC) results in long-term toxicities and increased physical and psychosocial survivor burden. There are a limited number of treatments for these late effects. Yoga postures, breath work, relaxation, and meditation, may improve these late effects. The purpose of this study was to examine the feasibility of a tailored yoga program in HNC survivors and obtain preliminary efficacy data.
This was a randomized wait-list control study of yoga-naive HNC survivors who were >3 months post-cancer treatment. Baseline data were collected. Participants were randomized to either an 8-week hatha yoga intervention group or a wait-list group. Feasibility and efficacy data were collected. At 4 and 8 weeks, patients underwent a repeat assessment of health. Wait-list control group participants were offered the yoga program after data collection. Descriptive statistics evaluated feasibility. Mixed effects general linear models were used to generate estimates of the efficacy outcomes.
Seventy-three individuals were screened and 40 were eligible. All eligible individuals consented and enrolled. Five of the intervention group discontinued early and none in the wait-list control group. Feasibility was affirmed as participants were recruited and retained in the study, there were no adverse events, fidelity to protocol was demonstrated, and satisfaction rates were high. Efficacy measures indicated potential benefit for shoulder range of motion ( d = 0.57-0.86, P < .05), pain ( d = 0.67-0.90, P ≤ .005), and anxiety ( d = 0.59, P = .015).
A tailored hatha yoga program is feasible and potentially efficacious for HNC survivors. Preliminary data supports further investigation of yoga in this population is needed.
头颈部癌症（HNC）的治疗会导致长期毒性以及身体和心理社会方面的生存者负担增加。针对这些晚期影响的治疗方法有限。瑜伽姿势、呼吸练习、放松和冥想可能会改善这些晚期影响。本研究的目的是研究针对 HNC 幸存者的量身定制瑜伽方案的可行性，并获得初步疗效数据。
这是一项针对癌症治疗后>3 个月的瑜伽新手 HNC 幸存者的随机等待名单对照研究。收集基线数据。参与者被随机分配到 8 周哈他瑜伽干预组或等待名单组。收集可行性和疗效数据。在第 4 周和第 8 周，患者接受了健康的重复评估。等待名单对照组在数据收集后提供瑜伽课程。使用描述性统计评估可行性。混合效应一般线性模型用于生成疗效结果的估计值。
共有 73 人接受了筛查，其中 40 人符合条件。所有符合条件的人均同意并参与。干预组中有 5 人提前退出，等待名单对照组中无人退出。可行性得到了肯定，因为参与者被招募并保留在研究中，没有不良事件，方案的一致性得到了证明，并且满意度很高。疗效指标表明，肩部活动范围（d = 0.57-0.86，P<.05）、疼痛（d = 0.67-0.90，P≤.005）和焦虑（d = 0.59，P=.015）方面有潜在的益处。
针对 HNC 幸存者的量身定制哈他瑜伽方案是可行的，并且可能具有疗效。初步数据支持需要进一步研究瑜伽在这一人群中的应用。
