Bandmann H J, Agathos M
Hautarzt. 1985 Dec;36(12):670-4.
Of 739 dermatitis patients, 4.1% showed a positive patch test reaction to benzoyl peroxide 1% in petrolatum. Forty-one patients with leg ulcers (patch test: negative to benzoyl peroxide) were treated with a 20% benzoyl peroxide emulsion for 4 weeks. After this therapy, the sensitization rate was as high as that for the maximization test, namely 76%. In most patients, the post-therapeutic allergy to benzoyl peroxide was accompanied by contact allergies to other therapeutic agents applied. Only 9 of 31 sensitized patients showed a monovalent benzoyl peroxide allergy. From the allergologic point of view, benzoyl peroxide cannot be recommended for the treatment of leg ulcers. However, there appears to be no danger in the treatment of acne vulgaris.
在739例皮炎患者中，4.1%的患者对凡士林基质中1%的过氧化苯甲酰斑贴试验呈阳性反应。41例腿部溃疡患者（斑贴试验：对过氧化苯甲酰呈阴性）接受了20%过氧化苯甲酰乳剂治疗4周。该治疗后，致敏率高达最大剂量试验的致敏率，即76%。在大多数患者中，治疗后对过氧化苯甲酰的过敏伴有对其他应用治疗剂的接触性过敏。31例致敏患者中只有9例表现为单一的过氧化苯甲酰过敏。从变态反应学角度来看，不推荐使用过氧化苯甲酰治疗腿部溃疡。然而，治疗寻常痤疮似乎没有危险。
