Odudu Leo A, Ezenwa Beatrice N, Esezobor Christopher I, Ekure Ekanem N, Egri Okwaji Mathias T C, Ezeaka Chinyere V, Njokanma Fidelis O, Ladele Jejelola
Department of Paediatrics, Lagos University Teaching Hospital, Idi-Araba, Nigeria.
Department of Paediatrics, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
Niger Postgrad Med J. 2017 Oct-Dec;24(4):224-229. doi: 10.4103/npmj.npmj_164_17.
Reference values of oxygen saturation (SpO2) to guide care of low birth weight neonates have been obtained mainly from Caucasians. Data from African newborns are lacking. To determine the pre- and post-ductal SpO2values of low birth weight neonates within the first 72 h of life, compare SpO2values of moderate-late preterm and term low birth weight neonates and determine how mode of delivery affected SpO2in the first 24 h of life.
An observational descriptive study was carried out on apparently healthy low birth weight newborns weighing 1500 to ≤2499 g. Pre and post ductal SpO2values were recorded at the following hours of life: 10-24 h, >24-48 h and >48-72 h using a NONIN® pulse oximeter.
The ranges of pre- and post-ductal SpO2in the study were similar for both preterm and term neonates in the study (89%-100%). The mean (standard deviation [SD]) pre-ductal SpO2was 95.9% (2.3) and the mean (SD) post-ductal SpO2was 95.9% (2.1). There was a significant increase in pre-ductal SpO2from 10 to 24 h through >48-72 h of life (P = 0.027). The mode of delivery did not affect SpO2values within 10-24 h of life.
The present study documented daily single pre- and post-ductal SpO2 values for preterm and term low birth weight neonates weighing 1500 g to <2500 g during the first 72 h of life. The overall range and mean pre- and post-ductal SpO2 were similar for both categories of stable low birth weight neonates in the study. There was no significant difference between SpO2ranges for late preterm compared to term low birth weight neonates. The results obtained could serve as guide in assessing SpO2of low birth weight neonates weighing between 1500 and 2499 g in the first 72 h of life.
用于指导低出生体重新生儿护理的血氧饱和度(SpO2)参考值主要来自白种人。缺乏非洲新生儿的数据。为了确定低出生体重新生儿出生后72小时内的导管前和导管后SpO2值,比较中度晚期早产儿和足月儿低出生体重新生儿的SpO2值,并确定分娩方式如何在出生后24小时内影响SpO2。
对体重1500至≤2499克的明显健康的低出生体重新生儿进行了一项观察性描述性研究。使用NONIN®脉搏血氧仪在以下生命时段记录导管前和导管后的SpO2值:出生后10 - 24小时、>24 - 48小时和>48 - 72小时。
研究中的早产儿和足月儿的导管前和导管后SpO2范围相似(89% - 100%)。导管前SpO2的平均值(标准差[SD])为95.9%(2.3),导管后SpO2的平均值(SD)为95.9%(2.1)。从出生后10至24小时到>48 - 72小时,导管前SpO2有显著增加(P = 0.027)。分娩方式在出生后10 - 24小时内不影响SpO2值。
本研究记录了体重1500克至<2500克的早产儿和足月儿低出生体重新生儿在出生后72小时内每日单次的导管前和导管后SpO2值。研究中两类稳定的低出生体重新生儿的总体导管前和导管后SpO2范围及平均值相似。晚期早产儿与足月儿低出生体重新生儿的SpO2范围之间无显著差异。所得结果可为评估出生后72小时内体重在1500至2499克之间的低出生体重新生儿的SpO2提供指导。