Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore.
Ann Acad Med Singap. 2017 Dec;46(12):461-469.
The World Health Organization Quality of Life (WHOQOL-BREF) questionnaire is a 26-item questionnaire that evaluates 4 domains of quality of life (QoL), namely Physical, Psychological, Social Relationships and Environment. This study aimed to evaluate the validity and reliability of the WHOQOL-BREF among Singapore residents aged 21 and above.
We recruited participants from the general population by using multistage cluster sampling and participants from 2 hospitals by using convenience sampling. Participants completed either English, Chinese or Malay versions of the WHOQOL-BREF and the EuroQoL 5 Dimension 5 Levels (EQ-5D-5L) questionnaires. Confirmatory factor analysis, known-group validity, internal consistency (Cronbach's alpha) and test-retest reliability using the intraclass correlation coefficient (ICC) were performed.
Data from 1316 participants were analysed (Chinese: 46.9%, Malay: 41.0% and Indian: 11.7%; 57.5% mean, mean standard deviation [SD, range] age: 51.9 [15.68, 24 to 90] years); 154 participants took part in the retest in various languages (English: 60, Chinese: 49 and Malay: 45). Tucker-Lewis Index (TLI) was 0.919, 0.913 and 0.909 for the English, Chinese and Malay versions, respectively. Cronbach's alpha exceeded 0.7 and ICC exceeded 0.4 for all domains in all language versions.
The WHOQOL-BREF is valid and reliable for assessing QoL in Singapore. Model fit is reasonable with room for improvement.
世界卫生组织生活质量（WHOQOL-BREF）问卷是一个包含 26 个项目的问卷，评估生活质量（QoL）的 4 个领域，即身体、心理、社会关系和环境。本研究旨在评估 WHOQOL-BREF 在新加坡 21 岁及以上居民中的有效性和可靠性。
我们通过多阶段聚类抽样从一般人群中招募参与者，并通过便利抽样从 2 家医院招募参与者。参与者完成 WHOQOL-BREF 和欧洲五维健康量表 5 级（EQ-5D-5L）问卷的英文、中文或马来文版本。进行验证性因子分析、已知组有效性、内部一致性（Cronbach's alpha）和使用组内相关系数（ICC）进行测试-重测信度。
分析了 1316 名参与者的数据（中文：46.9%，马来文：41.0%，印度文：11.7%；平均年龄 51.9 [15.68，24 至 90] 岁，平均标准差 [SD，范围]：51.9 [15.68，24 至 90] 岁）；154 名参与者以各种语言参加了重测（英语：60 人，中文：49 人，马来文：45 人）。英语、中文和马来文版本的 Tucker-Lewis 指数（TLI）分别为 0.919、0.913 和 0.909。所有语言版本的所有领域的 Cronbach's alpha 均超过 0.7，ICC 均超过 0.4。
WHOQOL-BREF 可有效可靠地评估新加坡的生活质量。模型拟合合理，仍有改进空间。
