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胰岛素治疗糖尿病患者全球人群中低血糖的直接和间接健康经济影响。

Direct and indirect health economic impact of hypoglycaemia in a global population of patients with insulin-treated diabetes.

机构信息

LMC Diabetes and Endocrinology, Toronto, Canada.

Endocrinology Research Center, Moscow, Russian Federation.

出版信息

Diabetes Res Clin Pract. 2018 Apr;138:35-43. doi: 10.1016/j.diabres.2018.01.007. Epub 2018 Jan 31.

Abstract

AIMS

The Hypoglycaemia Assessment Tool (HAT) study investigated the health economic impact of hypoglycaemic events in 24 countries, including countries without previously published data on hypoglycaemia.

METHODS

Self-assessment questionnaires and patient diaries (4-week prospective period) were completed by adults with type 1 (T1D) or type 2 diabetes (T2D) treated with insulin for more than 12 months (N = 27,585).

RESULTS

Direct economic impacts of hypoglycaemia during the 4-week prospective period, included increased blood glucose monitoring (reported by 69.7% [T1D] and 60.9% [T2D] of patients), hospitalisation (T1D 2.1%; T2D 3.4% of patients) and medical contact (clinic or telephone; T1D 3.8%; T2D 6.8% of patients). Regional variation in medical contact and hospitalisation was found, with the highest usage in Russia (T1D 17.1%; T2D 17.3%), and Latin America (T1D 5.2%; T2D 6.8%) respectively. Indirect economic impacts following hypoglycaemia included loss of productivity due to absence from work or study; 3.9% (T1D) and 6.2% (T2D) of patients. Regional differences in work productivity were noted among patients with T2D, with a low prevalence in Northern Europe and Canada (0.9%) and high in Southeast Asia (14.6%).

CONCLUSIONS

This study shows that hypoglycaemia has a significant but variable impact on the economics of diabetes healthcare globally.

摘要

目的

低血糖评估工具 (HAT) 研究调查了 24 个国家低血糖事件对健康经济的影响,其中包括以前没有发表过低血糖数据的国家。

方法

1 型 (T1D) 或 2 型 (T2D) 糖尿病患者接受胰岛素治疗超过 12 个月(N=27585)完成自我评估问卷和患者日记(4 周前瞻性时期)。

结果

4 周前瞻性期间低血糖的直接经济影响包括增加血糖监测(T1D 患者报告的比例为 69.7%,T2D 为 60.9%)、住院(T1D 为 2.1%;T2D 为 3.4%的患者)和医疗接触(诊所或电话;T1D 为 3.8%;T2D 为 6.8%的患者)。发现医疗接触和住院存在区域差异,俄罗斯(T1D 为 17.1%;T2D 为 17.3%)和拉丁美洲(T1D 为 5.2%;T2D 为 6.8%)的使用率最高。低血糖后还存在间接经济影响,包括因缺勤而导致的生产力损失;T1D 为 3.9%,T2D 为 6.2%的患者。还注意到 T2D 患者的工作生产力存在区域差异,北欧和加拿大的患病率较低(0.9%),东南亚较高(14.6%)。

结论

这项研究表明,低血糖对全球糖尿病医疗保健的经济具有重大但不同的影响。

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