Tekin Kemal, Sekeroglu Mehmet Ali, Kiziltoprak Hasan, Doguizi Sibel, Inanc Merve, Yilmazbas Pelin
Ophthalmology Department, Kars State Hospital, Kars, Turkey.
Ophthalmology Department, Ankara Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.
Clin Exp Optom. 2018 Sep;101(5):659-665. doi: 10.1111/cxo.12659. Epub 2018 Jan 21.
This study sought to determine normative static and dynamic pupillometry data in different age groups in a healthy population, and to investigate the effects of age on pupillometric characteristics.
Pupillometry measurements were undertaken on 155 healthy participants using an automatic quantitative pupillometry system. Static pupillometry measurements were undertaken; these included scotopic pupil diameter (PD), mesopic PD, low photopic PD and high photopic PD values. Dynamic pupillometry measurements were undertaken, including resting diameter, amplitude of pupil contraction, latency of pupil contraction, duration of pupil contraction, velocity of pupil contraction, latency of pupil dilation, duration of pupil dilation and velocity of pupil dilation.
Overall, 69 (44.5 per cent) participants were male and 86 (55.5 per cent) were female, with a mean age of 29.7 ± 17.8 years. Neither static nor dynamic pupillometry measurements varied significantly between males and females. Age was inversely and moderately correlated with each of the static pupillometric characteristics (p < 0.05). Resting diameter, velocity of pupil contraction, and velocity of pupil dilation values were inversely and moderately correlated with age (p < 0.001, r = -0.63; p < 0.001, r = -0.47; and p < 0.001, r = -0.34, respectively). Latency of pupil contraction was positively and moderately correlated with age (p = 0.002, r = 0.29).
The current study presents population-specific normative data on static and dynamic pupillometry values in different age groups and the effect of age on pupillary characteristics.
本研究旨在确定健康人群中不同年龄组的规范性静态和动态瞳孔测量数据，并研究年龄对瞳孔测量特征的影响。
使用自动定量瞳孔测量系统对155名健康参与者进行瞳孔测量。进行了静态瞳孔测量，包括暗视瞳孔直径（PD）、中间视觉PD、低明视PD和高明视PD值。进行了动态瞳孔测量，包括静息直径、瞳孔收缩幅度、瞳孔收缩潜伏期、瞳孔收缩持续时间、瞳孔收缩速度、瞳孔扩张潜伏期、瞳孔扩张持续时间和瞳孔扩张速度。
总体而言，69名（44.5%）参与者为男性，86名（55.5%）为女性，平均年龄为29.7±17.8岁。男性和女性之间的静态和动态瞳孔测量均无显著差异。年龄与每个静态瞳孔测量特征呈中度负相关（p<0.05）。静息直径、瞳孔收缩速度和瞳孔扩张速度值与年龄呈中度负相关（分别为p<0.001，r=-0.63；p<0.001，r=-0.47；p<0.001，r=-0.34）。瞳孔收缩潜伏期与年龄呈中度正相关（p=0.002，r=0.29）。
本研究提供了不同年龄组静态和动态瞳孔测量值的特定人群规范性数据以及年龄对瞳孔特征的影响。
