School of Pharmacy, Nantong University, 19 Qixiu Road, Nantong, Jiangsu Province, 226001, China.
Phytother Res. 2018 May;32(5):823-864. doi: 10.1002/ptr.6031. Epub 2018 Jan 22.
Central nervous system (CNS) disorders play a major impact on individual lives and place a severe strain on health care resources. Convolvulaceae is a family comprising approximately 1,600-1,700 species grouped in 55-60 genera, and many species are reported to have an effect on CNS functions. A systematic review of the literature studies was carried out to summarize available evidences on Convolvulaceae plants with CNS efficacies. This review is based on various data sources such as Google Scholar, Web of Science, Scopus, PubMed, and Wanfang Data. A total of 200 related articles were included in this review. According to the research result, 54 Convolvulaceae species are suggested to display CNS efficacies historically, and 46 species have been evaluated for their CNS efficacies. In addition, 67 compounds from 16 Convolvulaceae species are recognized to possess CNS efficacies. Despite great progress made through pharmacology and phytochemistry studies on CNS active Convolvulaceae species, more exploratory research is needed to gain a better understanding of the CNS efficacies of this plant family.
中枢神经系统（CNS）疾病对个人生活产生重大影响，并对医疗资源造成严重压力。旋花科是一个包含约 1600-1700 种植物的科，分为 55-60 属，许多物种被报道对 CNS 功能有影响。对具有 CNS 功效的旋花科植物的文献进行了系统综述，以总结现有证据。本综述基于多种数据源，如 Google Scholar、Web of Science、Scopus、PubMed 和万方数据。共有 200 篇相关文章纳入本综述。根据研究结果，历史上有 54 种旋花科植物被认为具有 CNS 功效，46 种已被评估其 CNS 功效。此外，从 16 种旋花科植物中鉴定出 67 种化合物具有 CNS 功效。尽管通过对具有 CNS 活性的旋花科植物的药理学和植物化学研究取得了很大进展，但仍需要更多的探索性研究来更好地了解该植物科的 CNS 功效。
