Takahashi Kana, Takada Koki, Hirao Kazuki
Department of Occupational Therapy, Kibi International University, Takahashi, Japan.
Early Interv Psychiatry. 2019 Feb;13(1):133-136. doi: 10.1111/eip.12540. Epub 2018 Jan 22.
We developed a motion picture-reproducing smartphone application (app) designed to improve self-confidence in individuals with subthreshold depression (StD) and examined the feasibility and preliminary efficacy of an app intervention for individuals with StD.
We conducted an open-label, single-arm pre-post study of 22 young adults with StD. Our intervention involved app usage for at least 70 min/wk for 5 weeks. The primary outcome measure was the adherence rate. Secondary outcome measures were safety and Center for Epidemiologic Studies Depression Scale (CES-D) scores.
No participants dropped out during the study. The adherence rate was 50%. The mean time of app use over 5 weeks was 124.23 ± 81.94 min/wk. No adverse events were reported. The CES-D scores were significantly improved at 5 weeks post-intervention.
Although this app intervention has the potential to reduce depressive symptoms, the app needs to be improved to increase adherence rates.
我们开发了一款旨在提高亚阈值抑郁症（StD）患者自信心的电影播放智能手机应用程序（应用），并研究了该应用干预对StD患者的可行性和初步疗效。
我们对22名患有StD的年轻成年人进行了一项开放标签、单臂前后对照研究。我们的干预措施包括连续5周每周使用该应用至少70分钟。主要结局指标是依从率。次要结局指标是安全性和流行病学研究中心抑郁量表（CES-D）得分。
研究期间无参与者退出。依从率为50%。5周内应用的平均使用时间为124.23±81.94分钟/周。未报告不良事件。干预后5周时，CES-D得分显著改善。
尽管这款应用干预有可能减轻抑郁症状，但需要对该应用进行改进以提高依从率。
