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中年成年人身体行为模式与抑郁症状、焦虑及幸福感水平之间的关联:一项使用等时替代模型的横断面研究

Associations between physical behaviour patterns and levels of depressive symptoms, anxiety and well-being in middle-aged adults: a cross-sectional study using isotemporal substitution models.

作者信息

Dillon Christina B, McMahon Elaine, O'Regan Grace, Perry Ivan J

机构信息

Department of Epidemiology and Public Health, HRB Centre for Diet and Health Research, University College Cork, Cork, Ireland.

National Suicide Research Foundation, University College Cork, Cork, Ireland.

出版信息

BMJ Open. 2018 Jan 21;8(1):e018978. doi: 10.1136/bmjopen-2017-018978.

DOI:10.1136/bmjopen-2017-018978
PMID:29358436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5781191/
Abstract

OBJECTIVE

To examine the compositional effects of physical behaviour on mental health.

DESIGN

Cross-sectional study.

SETTING

A population-representative random sample (Mitchelstown cohort) was recruited from a large primary care centre in Mitchelstown, County Cork, Ireland.

PARTICIPANTS

In total 3807 potential participants were selected from the practice list. Following exclusion of duplicates, deaths and ineligibles, 3043 were invited to participate and of these, 2047 (49.2% men) completed the questionnaire and physical examination components of the baseline assessment during the study period (April 2010 and May 2011). Accelerometers were introduced into the study in January 2011. Of the 745 participants seen between January and May of 2011, 475 (44.6% men) subjects (response rate 64%) agreed to participate and of these 397 (46.1% men) had valid accelerometer data.

PRIMARY AND SECONDARY OUTCOME MEASURES

Participants wore the wrist GENEActiv accelerometer for 7 consecutive days. Data were summarised into 60 s epochs and activity categorised as sedentary behaviour, light or moderate-to-vigorous physical activity (MVPA). Levels of depressive and anxiety symptoms were assessed using the Centre for Epidemiologic Studies Depression scale and the Hospital Anxiety and Depression Scale. Well-being was assessed using the WHO-5 well-being scale.

RESULTS

In adjusted isotemporal models, a 30 min increase in light activity per day was associated with a significant decrease in levels of anxiety symptoms (B=-0.34; 95% CI -0.64 to -0.04) and a significant increase in levels of well-being (B=0.58; 95% CI 0.05 to 1.11). No statistically significant associations were observed between any physical behaviour and depressive symptoms or when sedentary behaviour was substituted with MVPA (P>0.05).

CONCLUSION

Although based on a cross-sectional study, the findings suggest that substituting light activity for sedentary behaviour may have positive associations with symptoms of anxiety and reported well-being among middle-aged adults.

摘要

目的

研究身体行为的构成要素对心理健康的影响。

设计

横断面研究。

背景

从爱尔兰科克郡米切尔斯敦的一个大型初级保健中心招募具有人群代表性的随机样本(米切尔斯敦队列)。

参与者

从医疗机构名单中总共选取了3807名潜在参与者。排除重复、死亡及不符合条件者后,邀请了3043人参与,其中2047人(49.2%为男性)在研究期间(2010年4月至2011年5月)完成了基线评估的问卷调查和体格检查部分。2011年1月将加速度计引入研究。在2011年1月至5月期间见到的745名参与者中,475人(44.6%为男性)同意参与(应答率64%),其中397人(46.1%为男性)有有效的加速度计数据。

主要和次要结局指标

参与者连续7天佩戴腕部GENEActiv加速度计。数据汇总为60秒时段,活动分为久坐行为、轻度或中度至剧烈身体活动(MVPA)。使用流行病学研究中心抑郁量表和医院焦虑抑郁量表评估抑郁和焦虑症状水平。使用世界卫生组织-5幸福量表评估幸福感。

结果

在调整后的等时模型中,每天轻度活动增加30分钟与焦虑症状水平显著降低(B=-0.34;95%CI -0.64至-0.04)和幸福感水平显著提高(B=0.58;95%CI 0.05至1.11)相关。未观察到任何身体行为与抑郁症状之间或用MVPA替代久坐行为时有统计学显著关联(P>0.05)。

结论

尽管基于横断面研究,但研究结果表明,用轻度活动替代久坐行为可能与中年成年人的焦虑症状和报告的幸福感呈正相关。

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PLoS One. 2016 May 5;11(5):e0109913. doi: 10.1371/journal.pone.0109913. eCollection 2016.
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