Department of Ophthalmology, Kitasato University, Kanagawa, Japan.
School of Allied Health Sciences, Kitasato University, Kanagawa, Japan.
Sci Rep. 2018 Jan 22;8(1):1312. doi: 10.1038/s41598-018-20040-w.
This study was aimed to assess the predictability of intraocular lens (IOL) power calculation after cataract surgery for keratoconus. We retrospectively reviewed the clinical charts of 102 eyes of 71 consecutive keratoconic patients who developed cataract. We determined manifest spherical equivalent, prediction errors, and absolute errors, 1 month postoperatively. The achieved refraction was significantly more hyperopic than the targeted refraction, when keratometric readings were used (p = 0.001). At 1 month, 36% and 63% of the eyes were within ±0.5 and ±1.0 D, respectively, of the targeted correction. We found a significant correlation between the prediction error and the mean keratometry (Pearson correlation coefficient r =-0.545, p < 0.001). No vision-threatening complications occurred in any case. The achieved refraction was significantly more myopic than the targeted refraction, when total corneal refractive power was used (p = 0.013). Phacoemulsification with IOL implantation appeared to be safe and effective, and the accuracy was also good in mild keratoconus, but not in severe keratoconus. It should be noted that that a large amount of hyperopic shift occurred especially in advanced keratoconic patients, when keratometric readings were used for IOL power calculation, and that a slight, but significant, myopic shift occurred, when total corneal refractive power was used.
本研究旨在评估圆锥角膜患者白内障手术后人工晶状体(IOL)屈光力计算的可预测性。我们回顾性分析了 71 例连续圆锥角膜患者 102 只眼的临床资料,这些患者均发生白内障。我们在术后 1 个月时测量了实际球镜屈光度、预测误差和绝对误差。当使用角膜曲率计读数时,实际屈光度明显高于目标屈光度(p=0.001)。术后 1 个月时,36%和 63%的眼分别有 36%和 63%达到目标矫正值的±0.5 和±1.0 D 以内。我们发现预测误差与平均角膜曲率计读数之间存在显著相关性(Pearson 相关系数 r=-0.545,p<0.001)。在任何情况下均未发生视力威胁性并发症。当使用总角膜屈光力时,实际屈光度明显低于目标屈光度(p=0.013)。超声乳化白内障吸除联合 IOL 植入术安全有效,在轻度圆锥角膜中准确性也较好,但在重度圆锥角膜中则较差。需要注意的是,当使用角膜曲率计读数进行 IOL 屈光力计算时,尤其是在晚期圆锥角膜患者中,会发生大量远视漂移,而当使用总角膜屈光力时,则会发生轻微但显著的近视漂移。