Askgaard Gro, Neermark Søren, Leon David A, Kjær Mette S, Tolstrup Janne S
Department of Hepatology, Copenhagen University Hospital, Copenhagen Ø DK-2100, Denmark.
National Institute of Public Health, University of Southern Denmark, Copenhagen K DK-1353, Denmark.
World J Hepatol. 2017 Dec 28;9(36):1332-1339. doi: 10.4254/wjh.v9.i36.1332.
To evaluate prior hospital contacts with alcohol problems in patients with alcoholic liver cirrhosis and pancreatitis.
This was a register-based study of all patients diagnosed with alcoholic liver cirrhosis or pancreatitis during 2008-2012 in Denmark. Hospital contacts with alcohol problems (intoxication, harmful use, or dependence) in the 10-year period preceding the diagnosis of alcoholic liver cirrhosis and pancreatitis were identified.
In the 10 years prior to diagnosis, 40% of the 7719 alcoholic liver cirrhosis patients and 40% of the 1811 alcoholic pancreatitis patients had at least one prior hospital contact with alcohol problems. Every sixth patient (15%-16%) had more than five contacts. A similar pattern of prior hospital contacts was observed for alcoholic liver cirrhosis and pancreatitis. Around 30% were diagnosed with alcohol dependence and 10% with less severe alcohol diagnoses. For the majority, admission to somatic wards was the most common type of hospital care with alcohol problems. Most had their first contact with alcohol problems more than five years prior to diagnosis.
There may be opportunities to reach some of the patients who later develop alcoholic liver cirrhosis or pancreatitis with preventive interventions in the hospital setting.
评估酒精性肝硬化和胰腺炎患者之前因酒精问题的住院情况。
这是一项基于登记的研究，对象为2008年至2012年期间在丹麦被诊断为酒精性肝硬化或胰腺炎的所有患者。确定在酒精性肝硬化和胰腺炎诊断前10年期间因酒精问题（中毒、有害使用或依赖）的住院情况。
在诊断前的10年里，7719例酒精性肝硬化患者中有40%，1811例酒精性胰腺炎患者中有40%至少有一次因酒精问题的住院经历。每六名患者中就有一名（15%-16%）有超过五次的住院经历。酒精性肝硬化和胰腺炎患者之前的住院情况模式相似。约30%被诊断为酒精依赖，10%为酒精问题较轻的诊断。对于大多数人来说，入住躯体病房是因酒精问题最常见的住院类型。大多数人在诊断前五年多就首次接触到酒精问题。
在医院环境中，通过预防性干预措施可能有机会接触到一些后来发展为酒精性肝硬化或胰腺炎的患者。
