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金盐治疗引起的肺损伤。

Pulmonary injury induced by gold salts treatment.

作者信息

Schapira D, Nahir M, Scharf Y

出版信息

Med Interne. 1985 Oct-Dec;23(4):259-63.

PMID:2935924
Abstract

Pulmonary damage is one of the rare complications of gold salts therapy. The reaction is that of drug hypersensitivity. The clinical and radiological features as well as the respiratory function tests are that of an interstitial lung disease. This condition is described in four patients and its main features are discussed in the light of the relevant literature. The importance of an early diagnosis is emphasized. Most of the patients recover after the withdrawal of the drug and during corticosteroid treatment.

摘要

肺部损伤是金盐疗法罕见的并发症之一。这种反应属于药物超敏反应。临床、放射学特征以及呼吸功能测试均显示为间质性肺病。本文描述了4例该病症患者,并结合相关文献对其主要特征进行了讨论。强调了早期诊断的重要性。大多数患者在停药及接受皮质类固醇治疗后康复。

相似文献

1
Pulmonary injury induced by gold salts treatment.金盐治疗引起的肺损伤。
Med Interne. 1985 Oct-Dec;23(4):259-63.
2
[Gold therapy in chronic polyarthritis. Differentiation of allergic and toxic side effects].[慢性多关节炎的金疗法。过敏和毒性副作用的鉴别]
Z Rheumatol. 1980 Mar-Apr;39(3-4):109-16.
3
Letter: Pulmonary reaction to chrysotherapy.
N Engl J Med. 1976 Aug 26;295(9):506-7. doi: 10.1056/NEJM197608262950917.
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Gold reactions are not more common in Sjögren's syndrome.
Ann Intern Med. 1975 Jan;82(1):47-9. doi: 10.7326/0003-4819-82-1-47.
5
Mucocutaneous toxicity of gold salts by parenteral administration--rechallenge with auranofin.胃肠外给予金盐的皮肤黏膜毒性——用金诺芬再次激发试验
J Rheumatol. 1987 Feb;14(1):177.
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Comparative toxicity of gold preparations in treatment of rheumatoid arthritis.金制剂治疗类风湿关节炎的比较毒性
Ann Rheum Dis. 1976 Apr;35(2):171-3. doi: 10.1136/ard.35.2.171.
7
[Rare side effects of gold].
Z Rheumatol. 1986 May-Jun;45(3):107-10.
8
[Cutaneous side effects of gold therapy. Clinical and histologic results].
Z Rheumatol. 1986 May-Jun;45(3):100-6.
9
[Gold salt alveolitis in 3 patients with rheumatoid arthritis].
Pneumologie. 1995 Jun;49(6):367-72.
10
Gold-induced pneumonitis.金所致肺炎
Respiration. 1987;52(3):232-6. doi: 10.1159/000195330.

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