Lee C H, Morris T C
Pathology. 1979 Jul;11(3):551-6. doi: 10.3109/00313027909059030.
A patient with chronic myeloid leukaemia who developed widespread bone marrow necrosis associated wtih evolution of a new cell clone and with aggressive behaviour of the myeloid tumour in extramedullary sites is described. Cell necrosis in extramedullary tumours was also present; the sharp demarcation between zones of necrotic cells and intact cells and the histological evidence of vascular invasion by tumour cells suggest a vascular basis for cell necrosis.
描述了一名慢性髓性白血病患者，其发生了广泛的骨髓坏死，伴有新细胞克隆的演变以及髓系肿瘤在髓外部位的侵袭性表现。髓外肿瘤中也存在细胞坏死；坏死细胞区域与完整细胞之间的清晰界限以及肿瘤细胞血管侵袭的组织学证据提示细胞坏死的血管基础。
