Frolov A F, Rychnev V E, Frolov V M, Bala M A
Zh Mikrobiol Epidemiol Immunobiol. 1985 Nov(11):93-6.
The dynamics of circulating immune complexes (CIC) in comparison with the level of SH-groups of serum deproteinate and other characteristics of cell-mediated and humoral immunity (the reaction of the inhibition of antibodies, the levels of T-cells and their main subpopulations) was studied in 103 erysipelas patients and in 46 persons having had the disease at the acute period of this infection and at the periods between relapses. The elevated levels of CIC and SH-groups of serum deproteinate were found to be directly correlated with the inhibition index. The study showed that, as a rule, in patients with the elevated level of CIC the frequently relapsing form of erysipelas, accompanied by the formation of relative hypersuppressor-type secondary immunodeficiency and by a decrease in the functional activity of dermal macrophages, was observed.
对103例丹毒患者以及46例曾患丹毒且处于该感染急性期和复发间歇期的人员,研究了循环免疫复合物(CIC)的动态变化,并与血清脱蛋白中SH基团水平以及细胞介导免疫和体液免疫的其他特征(抗体抑制反应、T细胞水平及其主要亚群)进行了比较。发现CIC水平升高和血清脱蛋白中SH基团水平升高与抑制指数直接相关。研究表明,通常在CIC水平升高的患者中,观察到丹毒频繁复发的形式,伴有相对超抑制型继发性免疫缺陷的形成以及真皮巨噬细胞功能活性的降低。