Bala M A, Korabel'nikov S V
Zh Mikrobiol Epidemiol Immunobiol. 1993 Sep-Oct(5):83-7.
In this work 98 cases of streptococcal tonsillitis and 361 cases of erysipelas were studied. As revealed in this study, in relapsing forms of streptococcal infection antibodies to cross-reacting antigens of the infective agent appear in the blood. The synthesis of antibodies to the basal layers of skin epithelium was accompanied by an increase in the concentration of medium-size immune complexes, 0-cell population and by a decrease in the number of T suppressors. The mechanism of the development of the autoimmune process in relapsing forms of streptococcal infection is discussed.
在这项研究中，对98例链球菌性扁桃体炎和361例丹毒患者进行了研究。研究发现，在复发性链球菌感染中，血液中出现了针对感染病原体交叉反应抗原的抗体。针对皮肤上皮基层的抗体合成伴随着中等大小免疫复合物浓度的增加、0细胞群体的增加以及T抑制细胞数量的减少。本文还讨论了复发性链球菌感染中自身免疫过程的发展机制。
