Department of Radiology, Chonbuk National University Medical School and Hospital, Institute of Medical Science, Research Institute of Clinical Medicine, 20 Geonji-ro, Deokjin-gu, Jeonju City, Jeollabuk-Do 54907, South Korea.
Department of Statistics, Chonbuk National University, Research Institute of Applied Statistics, 567 Baekje-daero, Deokjin-gu, Jeonju City, Jeollabuk-Do 54896, South Korea.
Eur J Radiol. 2018 Feb;99:138-145. doi: 10.1016/j.ejrad.2018.01.002. Epub 2018 Jan 4.
To investigate the automated breast volume scanner (ABVS) in comparison with hand-held ultrasound (HHUS) according to the fifth edition of BI-RADS ultrasound.
A total of 831 lesions in 786 patients who underwent both HHUS and ABVS were included. Three radiologists independently evaluated the sonographic features of each lesion according to the fifth BI-RADS edition. The kappa coefficient (κ) was calculated for each BI-RADS descriptor and final assessment category. The accuracy of malignancy prediction and diagnostic performance of the BI-RADS descriptors were assessed using multivariate logistic regression and area under the receiver operator characteristic curve (AUC), respectively.
ABVS and HHUS showed moderate to good interobserver agreement (κ = 0.53-0.67 and 0.55-0.70, respectively) except in associated features (κ = 0.31 and 0.36, respectively) for BI-RADS lexicons. Irregular shape, a non-circumscribed margin, and posterior features (combined or shadowing) were independently associated with malignancy in both ABVS and HHUS. Calcification presence on ABVS (odds ratio [OR], 95% confidence interval [CI]: 2.09, 1.11-3.94) and non-parallel orientation on HHUS (OR, 95% CI: 2.04, 1.10-3.78) were independently associated with malignancy. There were no significant differences between ABVS and HHUS in sensitivity (84.2% vs. 84.2%), specificity (80.5% vs. 83.9%), or AUC (0.88 vs. 0.90).
According to the fifth BI-RADS edition, ABVS is not statistically significantly different from HHUS with regard to interobserver variability and diagnostic performance.
根据第五版 BI-RADS 超声标准，比较自动乳腺容积扫描仪（ABVS）与手持超声（HHUS）。
共纳入 786 例患者的 831 个病灶，这些患者均同时接受了 HHUS 和 ABVS 检查。三位放射科医生独立根据第五版 BI-RADS 标准评估每个病灶的超声特征。对于每个 BI-RADS 描述符和最终评估类别，计算了 Kappa 系数（κ）。使用多元逻辑回归和受试者工作特征曲线下面积（AUC）评估恶性肿瘤预测的准确性和 BI-RADS 描述符的诊断性能。
ABVS 和 HHUS 显示出中度到高度观察者间一致性（κ值分别为 0.53-0.67 和 0.55-0.70），但在关联特征方面（κ值分别为 0.31 和 0.36）除外。不规则形状、非边界清晰的边缘和后方特征（联合或阴影）在 ABVS 和 HHUS 中均与恶性肿瘤独立相关。ABVS 上的钙化存在（比值比[OR]，95%置信区间[CI]：2.09，1.11-3.94）和 HHUS 上的非平行取向（OR，95% CI：2.04，1.10-3.78）与恶性肿瘤独立相关。ABVS 和 HHUS 在敏感性（84.2%对 84.2%）、特异性（80.5%对 83.9%）或 AUC（0.88 对 0.90）方面没有显著差异。
根据第五版 BI-RADS 标准，ABVS 在观察者间变异性和诊断性能方面与 HHUS 没有统计学差异。
