Rotstein Barbara, Paululat Achim
Department of Zoology/Developmental Biology, University of Osnabrück, Osnabrück 49069, Germany.
J Cardiovasc Dev Dis. 2016 Apr 12;3(2):15. doi: 10.3390/jcdd3020015.
The circulatory system of represents an easily amenable genetic model whose analysis at different levels, , from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few examples. In recent years, the heart has also attracted the attention of researchers in the field of biomedicine. This development is mainly due to the fact that several genes causing human heart disease are also present in , where they play the same or similar roles in heart development, maintenance or physiology as their respective counterparts in humans. This review will attempt to briefly introduce the anatomy of the circulatory system and then focus on the different cell types and non-cellular tissue that constitute the heart.
[某种生物]的循环系统是一个易于研究的遗传模型,从单分子到功能解剖学等不同层面的分析,为心脏发生、心脏生理学和心脏衰老等一般方面提供了新的见解,仅举几个例子。近年来,[某种生物]的心脏也引起了生物医学领域研究人员的关注。这种发展主要是因为导致人类心脏病的几个基因在[某种生物]中也存在,它们在心脏发育、维持或生理学中发挥着与人类相应基因相同或相似的作用。本综述将试图简要介绍[某种生物]循环系统的解剖结构,然后重点关注构成心脏的不同细胞类型和非细胞组织。