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掌腱膜挛缩症患者的流行病学分析。

Epidemiological analysis of patients with Dupuytren's disease.

作者信息

Mansur Henrique Gonçalves, Oliveira Edmo Rodrigues de, Gonçalves Cesar Barbosa

机构信息

Departamento de Ortopedia e Traumatologia, Hospital Naval Marcílio Dias, Rio de Janeiro, RJ, Brazil.

出版信息

Rev Bras Ortop. 2017 Dec 14;53(1):10-14. doi: 10.1016/j.rboe.2017.12.003. eCollection 2018 Jan-Feb.

Abstract

OBJECTIVE

To evaluate the risk factors and analyze the characteristics of patients and lesions in Dupuytren's disease.

METHODS

Retrospective analysis of patients diagnosed with Dupuytren's disease in a hand surgery clinic in 2013. The authors evaluated parameters associated with the patient profiles and risk factors, the form and severity of involvement, and characteristics of the lesions.

RESULTS

58 patients were evaluated, totaling 79 hands, with bilateral involvement in 46% of cases. The involvement of the ulnar fingers of the hand represented 78%, 44% being the ring finger. In 55% of cases, the patients had cords, while 45% showed only nodules. As for related factors, they were found most commonly in men (55%), whites (93%), and the elderly. Of coexisting diseases, the following were present: diabetes mellitus (49%), especially in the insulin-dependent (62%), hypertension (55.2%), and dyslipidemia (19%). With regard to lifestyle, 22% were smokers and 9% were alcohol consumers.

CONCLUSION

It was observed a higher incidence of Dupuytren's disease was observed among men, whites, and the ulnar fingers of the hand, especially the ring finger. The most common associated diseases were diabetes mellitus and hypertension.

摘要

目的

评估掌腱膜挛缩症的危险因素,并分析患者及病变特征。

方法

回顾性分析2013年在一家手外科诊所诊断为掌腱膜挛缩症的患者。作者评估了与患者概况和危险因素、累及形式和严重程度以及病变特征相关的参数。

结果

共评估了58例患者,共计79只手,46%为双侧受累。手部尺侧手指受累占78%,其中无名指占44%。55%的病例患者有索条,45%仅表现为结节。至于相关因素,最常见于男性(55%)、白人(93%)和老年人。并存疾病有:糖尿病(49%),尤其是胰岛素依赖型(62%)、高血压(55.2%)和血脂异常(19%)。在生活方式方面,22%为吸烟者,9%为饮酒者。

结论

观察到掌腱膜挛缩症在男性、白人以及手部尺侧手指尤其是无名指中的发病率较高。最常见的并存疾病是糖尿病和高血压。

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本文引用的文献

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Dupuytren diathesis and genetic risk.
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Advances in the understanding of the aetiology of Dupuytren's disease.对迪普屈恩氏病病因的认识进展。
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Dupuytren's disease risk factors.杜普伊特伦挛缩症的风险因素。
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