Sonnenberg A, Sonnenberg G S
J Occup Med. 1986 Feb;28(2):87-90.
Although a general decline in the prevalence of duodenal ulcer disease during the past 20 to 30 years has been noticed by many authors from different countries, it still lacks a clear explanation. In the present paper a relationship between occupational work load and prevalence of peptic ulcer disease was examined in order to test the hypothesis that ulcer prevalence might be related to occupational work load. The number of disability pensions granted to West German employees between 1979 and 1983 due to gastric and duodenal ulcers served as markers of peptic ulcer morbidity and were used to analyze the relationship between occupation and prevalence of peptic ulcer disease. In men, there was a linear correlation between the energy expenditure of different occupations and the occurrence of duodenal ulcer, but not gastric ulcer. It appears that in gastric ulcer, compared with duodenal ulcer, additional factors related to occupational energy expenditure are relevant for the development of peptic ulceration. The decline of duodenal ulcer in Europe and the United States might be related to the general decline in the work load due to automation during the past 20 to 30 years. The relationship between energy expenditure and duodenal ulcer may also help to explain why the disease affects men two to three times more often than women.
尽管来自不同国家的许多作者都注意到在过去20至30年间十二指肠溃疡病的患病率普遍下降，但对此仍缺乏明确的解释。在本文中，研究了职业工作量与消化性溃疡病患病率之间的关系，以检验溃疡患病率可能与职业工作量相关这一假设。1979年至1983年间西德雇员因胃溃疡和十二指肠溃疡获得的残疾抚恤金数量用作消化性溃疡发病率的指标，并用于分析职业与消化性溃疡病患病率之间的关系。在男性中，不同职业的能量消耗与十二指肠溃疡的发生之间存在线性相关性，但与胃溃疡无关。与十二指肠溃疡相比，似乎在胃溃疡中，与职业能量消耗相关的其他因素与消化性溃疡的发生有关。欧美十二指肠溃疡的下降可能与过去20至30年间自动化导致的工作量普遍下降有关。能量消耗与十二指肠溃疡之间的关系也可能有助于解释为什么这种疾病在男性中的发病率比女性高出两到三倍。
