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[β-内啡肽对垂体激素分泌的作用机制]

[Mechanisms of action of beta-endorphin on the secretion of hypophyseal hormones].

作者信息

Slavnov V N, Valueva G V, Luchitskiĭ E V, Markov V V, Iakovlev A A

出版信息

Probl Endokrinol (Mosk). 1986 Jan-Feb;32(1):49-52.

PMID:2937051
Abstract

The purpose of the study was to investigate some mechanisms of the effect of beta-endorphin on somatotropic and lactotropic function of the hypophysis, adrenal activity and the content of catecholamines in the cerebral tissues. Activation of the hypophyseoadrenal system, lactotropic and somatotropic functions 5-20 min after beta-endorphin administration was established in experiments on male rats. At the same time a decrease in the content of catecholamines in the hypothalamus, cerebral cortex was observed. It was most significant for dopamine participating in the regulation of ACTH, prolactin and somatotropin secretion.

摘要

本研究的目的是探讨β-内啡肽对垂体生长激素和促乳素功能、肾上腺活动及脑组织中儿茶酚胺含量影响的一些机制。在雄性大鼠实验中证实,给予β-内啡肽后5 - 20分钟,垂体-肾上腺系统、促乳素和生长激素功能被激活。同时观察到下丘脑、大脑皮层中儿茶酚胺含量降低。这对参与促肾上腺皮质激素、催乳素和生长激素分泌调节的多巴胺影响最为显著。

相似文献

1
[Mechanisms of action of beta-endorphin on the secretion of hypophyseal hormones].[β-内啡肽对垂体激素分泌的作用机制]
Probl Endokrinol (Mosk). 1986 Jan-Feb;32(1):49-52.
2
[Effect of beta-endorphin on catecholamine levels in the rat hypothalamus and cerebral cortex].
Biull Eksp Biol Med. 1986 May;101(5):562-4.
3
Exercise-induced changes of endorphin contents in hypothalamus, hypophysis, adrenals and blood plasma.运动引起的下丘脑、垂体、肾上腺和血浆中内啡肽含量的变化。
Int J Sports Med. 1991 Oct;12(5):495-7. doi: 10.1055/s-2007-1024721.
4
[Effect of beta-endorphin on endocrine function].[β-内啡肽对内分泌功能的影响]
Biull Eksp Biol Med. 1983 Dec;96(12):5-7.
5
[Characteristics of the action of parlodel on endocrine functions of the body].[溴隐亭对机体内分泌功能的作用特点]
Farmakol Toksikol. 1986 Jul-Aug;49(4):54-7.
6
Rat plasma and hypothalamic beta-endorphin levels fluctuate concomitantly with plasma corticosteroids during the day.白天,大鼠血浆和下丘脑β-内啡肽水平与血浆皮质类固醇水平同步波动。
Acta Physiol Scand. 1982 Aug;115(4):515-6. doi: 10.1111/j.1748-1716.1982.tb07114.x.
7
Pituitary-adrenal activity and depletion of brain catecholamines after central administration of 6-hydroxydopamine.中枢给予6-羟基多巴胺后垂体-肾上腺活动及脑内儿茶酚胺耗竭
Res Commun Chem Pathol Pharmacol. 1973 Mar;5(2):263-71.
8
The calcium antagonist nimodipine increases beta-endorphin release from rat hypophysis through an action on adrenal glands. An "in vivo" and "in vitro" study.钙拮抗剂尼莫地平通过作用于肾上腺增加大鼠垂体β-内啡肽的释放。一项“体内”和“体外”研究。
Pharmacol Res Commun. 1984 Oct;16(10):959-68. doi: 10.1016/s0031-6989(84)80060-0.
9
Non-opiate beta-endorphin fragments and dopamine-V. gamma-Type endorphins and prolactin secretion in rats.非阿片β-内啡肽片段与多巴胺-V。大鼠体内γ型内啡肽与催乳素分泌
Neuropharmacology. 1982 Nov;21(11):1129-35. doi: 10.1016/0028-3908(82)90170-8.
10
Dopaminergic mediation of beta-endorphin-induced prolactin secretion.多巴胺能介导β-内啡肽诱导的催乳素分泌。
Neuroendocrinology. 1980 Oct;31(4):293-6.

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