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13 岁时的乳制品和总钙摄入量及其与 21 岁时肥胖的关系。

Dairy products and total calcium intake at 13 years of age and its association with obesity at 21 years of age.

机构信息

Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, Porto, Portugal.

EPIUnit, Institute of Public Health (ISPUP), University of Porto, Porto, Portugal.

出版信息

Eur J Clin Nutr. 2018 Apr;72(4):541-547. doi: 10.1038/s41430-017-0082-x. Epub 2018 Jan 25.

Abstract

BACKGROUND/OBJECTIVES: Dairy products and specifically calcium have been suggested to play a role in obesity development but more longitudinal evidence is still needed. The objective of this study was to assess the association between dairy products and total calcium intake at age 13 and body mass index at age 21.

SUBJECTS/METHODS: This longitudinal study included 2159 individuals from the Epidemiological Health Investigation of Teenagers cohort (EPITeen), Porto, Portugal, evaluated at ages 13 and 21. Assessment consisted of anthropometrics measurements and structured questionnaires namely a semi-quantitative food frequency questionnaire to appraise food consumption in the past 12 months. Linear regression models were run in 941 individuals with complete information of confounders: gender, follow-up period, parents' education, physical activity, energy, and total calcium intake.

RESULTS

Negative association was found on total calcium intake at age 13 with BMI at age 21 (model 0: β = -0.059 (95% CI: -0.113, -0.004) and model 1: -0.057 (95% CI: -0.113, -0.002)), however, no statistically significant association was found when adjusting for energy intake (model 2: β = -0.031 (95% CI: -0.110, 0.047). There were no associations between milk, yogurt, and cheese consumption at age 13 and BMI at age 21 when adjusting for confounders.

CONCLUSIONS

This study did not support an independent effect of dairy products or total calcium intake in adolescence on later early adulthood adiposity.

摘要

背景/目的:乳制品,尤其是钙,被认为与肥胖的发展有关,但仍需要更多的纵向证据。本研究的目的是评估 13 岁时乳制品和总钙摄入量与 21 岁时体重指数之间的关系。

受试者/方法:这项纵向研究包括来自葡萄牙波尔图的青少年流行病学健康调查(EPITeen)队列的 2159 名个体,他们在 13 岁和 21 岁时接受了评估。评估包括人体测量学测量和结构化问卷,即半定量食物频率问卷,以评估过去 12 个月的食物消耗情况。在 941 名具有完整混杂因素信息的个体中运行线性回归模型:性别、随访期、父母教育程度、体力活动、能量和总钙摄入量。

结果

13 岁时的总钙摄入量与 21 岁时的 BMI 呈负相关(模型 0:β=-0.059(95%CI:-0.113,-0.004)和模型 1:-0.057(95%CI:-0.113,-0.002)),然而,当调整能量摄入量时,没有发现统计学上的显著相关性(模型 2:β=-0.031(95%CI:-0.110,0.047)。当调整混杂因素时,13 岁时的牛奶、酸奶和奶酪摄入量与 21 岁时的 BMI 之间没有关联。

结论

本研究不支持青少年时期乳制品或总钙摄入量对以后成年早期肥胖的独立影响。

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