Choi Hyun Joung, Bae Yoon Joo, Choi June Seek, Ahn Hun Kyong, An Hyun Sook, Hong Dal Soo, Yun Jeong-Sup, Han Jung Yeol
Korean Motherisk Program, Seoul, Korea.
Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Dankook University College of Medicine, Seoul, Korea.
Obstet Gynecol Sci. 2018 Jan;61(1):30-37. doi: 10.5468/ogs.2018.61.1.30. Epub 2017 Dec 14.
Severity of nausea and vomiting of pregnancy (NVP) is associated with adverse pregnancy outcomes and poorer quality of life (QOL). The aim of this study was to evaluate the severity of NVP and maternal well-being status using the Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scale in a Korean population.
A total of 527 pregnant women who were receiving prenatal care at 4 hospitals were asked to participate in the study between January 2015 and June 2015. The severity of NVP was evaluated by the PUQE scale and maternal well-being status was evaluated using the visual analogue scale (VAS). Statistical analyses were performed to determine the risk factors associated with NVP and the associations between the severity of NVP and QOL.
Among the 472 eligible pregnant women, 381 (80.7%) were suffering from NVP during pregnancy. No significant differences (>0.05) were observed in any of the variables between the 2 study groups, with the exception of smoking, alcohol consumption, and history of NVP. NVP history was found to be the most powerful risk factor (adjusted odds ratio, 11.6; 95% confidence interval, 4.7-28.7). The correlation coefficient () between the VAS scores of maternal well-being status and PUQE severity was -0.25 (=0.062; <0.001).
In this study, an explicit decline in maternal well-being status was observed according to severity of NVP. The PUQE scale may be of help to clinicians, healthcare providers, and researchers because of its simplicity and usefulness as a tool for NVP evaluation.
妊娠恶心和呕吐(NVP)的严重程度与不良妊娠结局及较差的生活质量(QOL)相关。本研究的目的是使用妊娠呕吐和恶心独特量化(PUQE)量表评估韩国人群中NVP的严重程度及母亲的健康状况。
2015年1月至2015年6月期间,邀请了在4家医院接受产前护理的527名孕妇参与本研究。通过PUQE量表评估NVP的严重程度,并使用视觉模拟量表(VAS)评估母亲的健康状况。进行统计分析以确定与NVP相关的危险因素以及NVP严重程度与生活质量之间的关联。
在472名符合条件的孕妇中,381名(80.7%)在孕期患有NVP。除吸烟、饮酒和NVP病史外,两个研究组在任何变量上均未观察到显著差异(>0.05)。发现NVP病史是最有力的危险因素(调整后的优势比为11.6;95%置信区间为4.7 - 28.7)。母亲健康状况的VAS评分与PUQE严重程度之间的相关系数()为 - 0.25(=0.062;<0.001)。
在本研究中,根据NVP的严重程度观察到母亲健康状况明显下降。由于PUQE量表作为评估NVP的工具具有简单性和实用性,它可能对临床医生、医疗保健提供者和研究人员有所帮助。