Gould Fraser John
British Antarctic Survey Medical Unit, South Georgia & the South Sandwich Islands.
Wilderness Environ Med. 2018 Mar;29(1):102-110. doi: 10.1016/j.wem.2017.09.013. Epub 2018 Jan 17.
Acute shoulder dislocation is a common injury in the outdoor environment. The objective of this systematic review of the literature was to determine if intra-articular local anesthetic (IAL) is an effective treatment that could have prehospital application. A methodical search of MEDLINE, PubMed, and EMBASE databases targeted publications from January 1, 1990 until January 1, 2017. Eligible articles compared IAL with other analgesic techniques in patients 16 years or older experiencing acute glenohumeral dislocation. Reduction success, complications, and patient-reported outcome measures underwent comparison. All identified publications originated from the hospital setting. Procedural success rates ranged widely among randomized control trials comparing IAL with intravenous analgesia and sedation (IAL 48-100%, intravenous analgesia and sedation 44-100%). A pooled risk ratio [RR] favored intravenous analgesia and sedation (RR 0.91, 95% confidence interval [CI] 0.84-0.98), but there was significant inconsistency within the analysis (I = 75%). IAL provided lower complication rates (4/170, 2%) than intravenous analgesia and sedation (20/150, 13%) (RR 1.11, 95% CI 1.04-1.19, I = 63%). One trial found a clinically relevant reduction in visual analogue pain scores when comparing IAL against no additional analgesia in the first minute (IAL 21±13 mm; control 49±15 mm; P<0.001) and fifth minute (IAL 10±10 mm; control 40±14 mm, P<0.001) after reduction. The results suggest that IAL is an effective intervention for acute anterior shoulder dislocation that would have a place in the repertoire of the remote physician. Further research might be beneficial in determining the outcomes of performing IAL in the prehospital setting.
急性肩关节脱位是户外环境中常见的损伤。本系统文献综述的目的是确定关节内局部麻醉(IAL)是否为一种可在院前应用的有效治疗方法。对MEDLINE、PubMed和EMBASE数据库进行了系统检索,目标是1990年1月1日至2017年1月1日期间发表的文献。符合条件的文章比较了16岁及以上急性肩肱关节脱位患者使用IAL与其他镇痛技术的情况。对复位成功率、并发症及患者报告的结局指标进行了比较。所有纳入的文献均来自医院环境。在比较IAL与静脉镇痛镇静的随机对照试验中,手术成功率差异很大(IAL为48%-100%,静脉镇痛镇静为44%-100%)。合并风险比[RR]支持静脉镇痛镇静(RR 0.91,95%置信区间[CI] 0.84-0.98),但分析中存在显著异质性(I² = 75%)。IAL的并发症发生率(4/170,2%)低于静脉镇痛镇静(20/150,13%)(RR 1.11,95% CI1.04-1.19,I² = 63%)。一项试验发现,复位后第一分钟(IAL 21±13 mm;对照组49±15 mm;P<0.001)和第五分钟(IAL 10±10 mm;对照组40±14 mm,P<0.001),IAL与不使用额外镇痛措施相比,视觉模拟疼痛评分有临床意义的降低。结果表明,IAL是急性前肩关节脱位的有效干预措施,远程医生可将其纳入治疗方法。进一步的研究可能有助于确定在院前环境中实施IAL的效果。