From the Department of Neurology, Kyungpook National University, School of Medicine, Daegu, South Korea (J-SP); Department of Rehabilitation Medicine, Daegu Fatima Hospital, Daegu, South Korea (DP); and Department of Pharmacology, Kyungpook National University, School of Medicine, Daegu, South Korea (DP).
Am J Phys Med Rehabil. 2018 Oct;97(10):e93-e95. doi: 10.1097/PHM.0000000000000901.
Ultrasound-guided corticosteroid injection into the carpal tunnel is widely performed for the management of carpal tunnel syndrome. However, this injection may worsen the condition in patients with type 2 diabetes mellitus. Polydeoxyribonucleotide was recently recognized as a substitute for corticosteroid because of its anti-inflammatory effects. A 41-yr-old woman with type 2 diabetes mellitus was admitted to our rehabilitation clinic with a 1-mo history of numbness and tingling in her right hand and first three fingers tips. She declined corticosteroid treatment because of a previous episode of uncontrolled blood glucose levels after corticosteroid injection. Therefore, ultrasound-guided polydeoxyribonucleotide injections into the carpal tunnel were carried out. At the 6-mo follow-up, the patient demonstrated an improvement in the carpal tunnel syndrome symptoms without any complications. Thus, polydeoxyribonucleotide injections into the carpal tunnel can be an alternative to corticosteroid injections for carpal tunnel syndrome if there are limitations because of adverse effects of the latter.
超声引导下腕管内皮质类固醇注射广泛应用于治疗腕管综合征。然而，这种注射可能会使 2 型糖尿病患者的病情恶化。多聚脱氧核苷酸因其抗炎作用而被认为是皮质类固醇的替代品。一名 41 岁女性，患有 2 型糖尿病，右手和前三个手指指尖麻木刺痛 1 个月，入我院康复科就诊。由于之前皮质类固醇注射后血糖水平失控的发作，她拒绝接受皮质类固醇治疗。因此，进行了超声引导下的多聚脱氧核苷酸腕管内注射。在 6 个月的随访中，患者的腕管综合征症状得到改善，无任何并发症。因此，如果由于后者的不良反应而存在限制，多聚脱氧核苷酸腕管内注射可以替代皮质类固醇注射治疗腕管综合征。
