Harper Ashton, Naghibi Malwina M, Garcha Davinder
Protexin, Medical Affairs, Probiotics International Ltd., Lopen Head, Somerset TA13 5JH, UK.
Foods. 2018 Jan 26;7(2):13. doi: 10.3390/foods7020013.
Irritable bowel syndrome is a highly prevalent gastrointestinal disorder that threatens the quality of life of millions and poses a substantial financial burden on healthcare systems around the world. Intense research into the human microbiome has led to fascinating discoveries which directly and indirectly implicate the diversity and function of this occult organ in irritable bowel syndrome (IBS) pathophysiology. The benefit of manipulating the gastrointestinal microbiota with diet and probiotics to improve symptoms has been demonstrated in a wealth of both animal and human studies. The positive and negative mechanistic roles bacteria play in IBS will be explored and practical probiotic and dietary choices offered.
肠易激综合征是一种高度流行的胃肠道疾病,威胁着数百万人的生活质量,并给全球医疗系统带来沉重的经济负担。对人类微生物群的深入研究带来了一些引人入胜的发现,这些发现直接或间接地表明这个隐匿器官的多样性和功能与肠易激综合征(IBS)的病理生理学有关。大量动物和人体研究已证明,通过饮食和益生菌调节胃肠道微生物群以改善症状是有益的。本文将探讨细菌在IBS中发挥的正负机制作用,并提供实用的益生菌和饮食选择建议。