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通过饮食摄入常量碘可能改善甲状腺功能减退症的治疗:病例报告。

Constant iodine intake through the diet could improve hypothyroidism treatment: a case report.

机构信息

Laboratorio de Higiene, Inspección y Control de Alimentos, Facultad de Veterinaria, Departamento de Química Analítica, Nutrición y Bromatología, Universidad de Santiago de Compostela, Pab4, planta baja. c/Campus universitario, s/n, 27002, Lugo, Spain.

出版信息

J Physiol Biochem. 2018 Feb;74(1):189-193. doi: 10.1007/s13105-017-0605-x. Epub 2018 Jan 26.

DOI:10.1007/s13105-017-0605-x
PMID:29374374
Abstract

Currently, hypothyroidism is usually treated only with drugs; patients are never told that they could regulate their levels of iodine with dietary recommendations in a complementary way. The objective of this work was to explore the effect of a constant iodine intake through the diet in a postmenopausal woman with subclinical grade II hypothyroidism, who also had mild hypercholesterolemia and obesity. Baseline anthropometric nutritional, pharmacological, and habit data were obtained, then the woman was scheduled for 1 month a diet in which she was provided food naturally containing iodine, so that the recommended requirements (iodine 150 μg/day) were met. All the information about which foods contain this mineral was supplied and explained to the patient. This diet was also designed to help her to gradually lose weight, and was more balanced and closer to the nutritional recommendations. The results obtained in this work were satisfactory, having achieved improved blood levels of thyroid-stimulating hormone (1.78 μIU/mL) and reduced total cholesterol levels (198 mg/dL). Statement of hypercholesterolemia was demoted. In addition, a significant improvement in relation to weight and body volume was reached (body mass index fell from 30.13 to 28.5 kg/m), an important fact since it has impacted the overall well-being of the patient. In conclusion, it was demonstrated that a constant iodine intake through the diet for this patient with grade II hypothyroidism was very effective, and therefore, this aspect should be also considered during hypothyroidism treatment.

摘要

目前,甲状腺功能减退症通常仅用药物治疗;从未告知患者,他们可以通过饮食建议以补充的方式来调节碘的水平。本工作的目的是探讨通过饮食持续摄入碘对患有亚临床 2 级甲状腺功能减退症、轻度高胆固醇血症和肥胖的绝经后妇女的影响。获取了基线人体测量营养、药物和习惯数据,然后安排该妇女进行为期 1 个月的饮食,其中提供天然含碘食物,以满足推荐的需求(碘 150μg/天)。向患者提供了有关哪些食物含有这种矿物质的所有信息并进行了说明。该饮食还旨在帮助她逐渐减轻体重,使饮食更均衡并更接近营养建议。本工作的结果令人满意,甲状腺刺激激素的血液水平得到改善(1.78μIU/mL),总胆固醇水平降低(198mg/dL)。高胆固醇血症的诊断降级。此外,体重和体脂率显著改善(体重指数从 30.13 降至 28.5kg/m,这是一个重要事实,因为它影响了患者的整体健康状况。总之,证明了通过饮食持续摄入碘对患有 2 级甲状腺功能减退症的患者非常有效,因此,在治疗甲状腺功能减退症时也应考虑这一方面。

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本文引用的文献

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The importance of iodine in public health.碘在公共卫生中的重要性。
Environ Geochem Health. 2015 Aug;37(4):605-18. doi: 10.1007/s10653-015-9681-4. Epub 2015 Feb 7.
2
Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.成人甲状腺功能减退症临床实践指南:由美国临床内分泌医师学会和美国甲状腺协会共同赞助。
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Iodine excess.碘过量。
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