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与孕产妇接近死亡相关的远因和近因:埃塞俄比亚亚的斯亚贝巴部分公立医院的一项巢式病例对照研究。

Distant and proximate factors associated with maternal near-miss: a nested case-control study in selected public hospitals of Addis Ababa, Ethiopia.

作者信息

Liyew Ewnetu Firdawek, Yalew Alemayehu Worku, Afework Mesganaw Fantahun, Essén Birgitta

机构信息

Department of Nursing, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.

Department of Preventive Medicine, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

BMC Womens Health. 2018 Jan 27;18(1):28. doi: 10.1186/s12905-018-0519-y.

Abstract

BACKGROUND

Ethiopia is one of the sub-Saharan Africa countries with the highest maternal mortality. Maternal near-misses are more common than deaths and statistically stronger for a comprehensive analysis of the determinants. The study aimed to identify the factors associated with maternal near-miss in selected public hospitals of Addis Ababa, Ethiopia.

METHODS

We conducted a nested case-control study in five selected public hospitals of Addis Ababa, Ethiopia from May 1, 2015 to April 30, 2016. Participants were interviewed by well-trained data collectors using pre-tested questionnaire. Medical records were also reviewed to gather relevant information. World Health Organization criteria were used to identify maternal near-miss cases. A total of three controls matched for age and study area was selected for each maternal near-miss case. Bivariate and multivariable conditional logistic regressions were performed using Stata version 13.0.

RESULTS

A total of 216 maternal near-miss cases and 648 controls were included in the study. The main factors associated with maternal near-miss were: history of chronic hypertension (AOR = 10.80,95% CI; 5.16-22.60), rural residency (AOR = 10.60,95% CI;4.59-24.46), history of stillbirth (AOR = 6.03,95% CI;2.09-17.41), no antenatal care attendance (AOR = 5.58,95% CI;1.94-16.07) and history of anemia (AOR = 5.26,95% CI;2.89-9.57).

CONCLUSIONS

There is a need for appropriate interventions in order to improve the identified factors. The factors can be modified through a better access to medical and maternity care, scaling up of antenatal care in rural areas, improve in infrastructure to fulfill referral chain from primary level to secondary and tertiary health care levels, and health education to pregnant women.

摘要

背景

埃塞俄比亚是撒哈拉以南非洲孕产妇死亡率最高的国家之一。孕产妇接近死亡的情况比死亡更为常见,且从统计学角度来看,对于全面分析决定因素而言更为有力。该研究旨在确定埃塞俄比亚亚的斯亚贝巴选定公立医院中与孕产妇接近死亡相关的因素。

方法

2015年5月1日至2016年4月30日,我们在埃塞俄比亚亚的斯亚贝巴选定的五家公立医院开展了一项巢式病例对照研究。由训练有素的数据收集员使用预先测试过的问卷对参与者进行访谈。还查阅了医疗记录以收集相关信息。采用世界卫生组织的标准来确定孕产妇接近死亡病例。为每例孕产妇接近死亡病例选取了总共三名年龄和研究区域匹配的对照。使用Stata 13.0版本进行二元和多变量条件逻辑回归分析。

结果

该研究共纳入了216例孕产妇接近死亡病例和648名对照。与孕产妇接近死亡相关的主要因素有:慢性高血压病史(比值比=10.80,95%置信区间;5.16 - 22.60)、农村居住情况(比值比=10.60,95%置信区间;4.59 - 24.46)、死产史(比值比=6.03,95%置信区间;2.09 - 17.41)、未进行产前检查(比值比=5.58,95%置信区间;1.94 - 16.07)以及贫血史(比值比=5.26,95%置信区间;2.89 - 9.57)。

结论

需要采取适当干预措施来改善已确定的因素。这些因素可通过更好地获得医疗和产科护理、扩大农村地区的产前检查、改善基础设施以完善从初级到二级和三级医疗保健水平的转诊链以及对孕妇进行健康教育来加以改善。

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