Adamaszek Michael, D'Agata Federico, Steele Christopher J, Sehm Bernhard, Schoppe Cornelia, Strecker Karl, Woldag Hartwig, Hummelsheim Horst, Kirkby Kenneth C
a Department of Clinical and Cognitive Neurorehabilitation , Klinik Bavaria Kreischa , Kreischa , Germany.
b Department of Neuroscience , AOU San Giovanni Battista Turin , Turin , Italy.
Soc Neurosci. 2019 Apr;14(2):195-207. doi: 10.1080/17470919.2018.1434089. Epub 2018 Feb 15.
Widespread cortical-subcortical networks are involved in the recognition and discrimination of emotional contents of facial and vocal expression, whereby the cerebellum and basal ganglia are two subcortical regions implicated in these networks with limited evidence to their specific contributions. To investigate this we compared patients with circumscribed cerebellar lesions and patients with Parkinson's disease (PD) on an approved test battery. We studied two groups with subcortical disease, focal cerebellar infarction (n = 22) and PD (n = 22), and a neurological control group with focal supratentorial ischemia (SI) (n = 16) were. Assessments were according to inpatient protocols for neuropsychological routine evaluation, including tests of memory, executive function and attention. Participants completed the Tuebingen Affect Battery, a recognized measure of recognition and discrimination of facial and vocal expression of emotion. As a result, cerebellar lesions were associated with greater impairment than PD and SI in recognition and discrimination of cues of both facial and vocal expressions of differing basic emotions. No confounding effect of other cognitive domains, particularly executive function and attention, was found. Taken together, our findings suggest a specific contribution of the cerebellum to cerebral networks that process facial and vocal emotion expression, related to rapid decisions regulating appropriate behavioral responses in social environments.
广泛的皮层 - 皮层下网络参与面部和声音表情情感内容的识别与辨别，其中小脑和基底神经节是这些网络中涉及的两个皮层下区域，但关于它们具体贡献的证据有限。为了对此进行研究，我们在一个经过批准的测试组中对比了患有局限性小脑病变的患者和帕金森病（PD）患者。我们研究了两组患有皮层下疾病的患者，局灶性小脑梗死患者（n = 22）和PD患者（n = 22），以及一个患有幕上局灶性缺血（SI）的神经对照组（n = 16）。评估是根据神经心理学常规评估的住院患者方案进行的，包括记忆、执行功能和注意力测试。参与者完成了图宾根情感测试组，这是一种公认的对面部和声音情感表达进行识别和辨别的测量方法。结果显示，在识别和辨别不同基本情绪的面部和声音表达线索方面，小脑病变比PD和SI导致的损伤更大。未发现其他认知领域，特别是执行功能和注意力的混杂效应。综上所述，我们的研究结果表明小脑对处理面部和声音情感表达的大脑网络有特定贡献，这与在社交环境中调节适当行为反应的快速决策有关。
