Fisher James N, Tessaro Irene, Bertocco Tommaso, Peretti Giuseppe M, Mangiavini Laura
IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.
Università Vita-Salute San Raffaele, Milan, Italy.
Stem Cells Int. 2017;2017:2761678. doi: 10.1155/2017/2761678. Epub 2017 Dec 10.
The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic level. Tissue engineering and regenerative medicine using stem/progenitor cells have emerged as valid alternatives to classical reparative techniques. This review offers a brief introduction and overview of the field, highlighting a number of tissue sources for stem/progenitor cell populations. Emphasis is given to recent developments in both clinical and basic sciences. The relative strengths and weaknesses of each tissue type are discussed.
关节软骨退变在临床和基础研究层面都是一个持续存在的挑战。利用干/祖细胞的组织工程和再生医学已成为传统修复技术的有效替代方案。本文献综述对该领域进行了简要介绍和概述,重点介绍了一些干/祖细胞群体的组织来源。着重阐述了临床和基础科学的最新进展。讨论了每种组织类型的相对优缺点。