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不同组织来源的干细胞在软骨修复中的应用

The Application of Stem Cells from Different Tissues to Cartilage Repair.

作者信息

Fisher James N, Tessaro Irene, Bertocco Tommaso, Peretti Giuseppe M, Mangiavini Laura

机构信息

IRCCS Istituto Ortopedico Galeazzi, 20161 Milan, Italy.

Università Vita-Salute San Raffaele, Milan, Italy.

出版信息

Stem Cells Int. 2017;2017:2761678. doi: 10.1155/2017/2761678. Epub 2017 Dec 10.

Abstract

The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic level. Tissue engineering and regenerative medicine using stem/progenitor cells have emerged as valid alternatives to classical reparative techniques. This review offers a brief introduction and overview of the field, highlighting a number of tissue sources for stem/progenitor cell populations. Emphasis is given to recent developments in both clinical and basic sciences. The relative strengths and weaknesses of each tissue type are discussed.

摘要

关节软骨退变在临床和基础研究层面都是一个持续存在的挑战。利用干/祖细胞的组织工程和再生医学已成为传统修复技术的有效替代方案。本文献综述对该领域进行了简要介绍和概述,重点介绍了一些干/祖细胞群体的组织来源。着重阐述了临床和基础科学的最新进展。讨论了每种组织类型的相对优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f820/5742463/9572494c7453/SCI2017-2761678.001.jpg

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