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胆总管结石内镜下胆道支架置入术的管理:支架更换间隔的评估

Management of endoscopic biliary stenting for choledocholithiasis: Evaluation of stent-exchange intervals.

作者信息

Tohda Gen, Dochin Masaki

机构信息

Department of Gastroenterology, Fukui Kosei Hospital, Fukui 918-8537, Japan.

出版信息

World J Gastrointest Endosc. 2018 Jan 16;10(1):45-50. doi: 10.4253/wjge.v10.i1.45.

Abstract

AIM

To evaluate the best management of plastic stents in patients with choledocholithiasis who were unfit for endoscopic stone removal or surgery.

METHODS

Between April 2007 and September 2017, 87 patients (median age 83.7 years) with symptomatic choledocholithiasis were treated with insertion of 7-Fr plastic stents because complete endoscopic stone retrieval was difficult, and their general condition was not suitable for surgery. Seventy of these patients agreed to regular stent management and stent exchange was carried out at every 6 mo (Group A, = 35) or every 12 mo (Group B, = 35). The remaining 17 patients did not accept regular stent exchange, and stents were replaced when clinical symptoms appeared (Group C). We evaluated the frequency of biliary complication and stent patency rate during follow-up periods.

RESULTS

The patency rate of biliary plastic stents was 91.4% at 6 mo (Group A) and 88.6% at 12 mo (Group B), respectively. Acute cholangitis occurred in 2.9% of Group A patients and in 8.6% of Group B patients. In Group C, median stent patency was 16.3 mo, and stent exchange was carried out in 70.6% of cases because of acute cholangitis or obstructive jaundice. Although a high incidence of acute cholangitis occurred, there was no biliary-related mortality.

CONCLUSION

Plastic stent exchange at 12-mo intervals is considered a safe procedure for patients with choledocholithiasis. Long-term biliary stenting increases biliary complications, but it can be an acceptable option for select patients who are medically unfit for further invasive procedures.

摘要

目的

评估对于不宜进行内镜取石或手术的胆总管结石患者,塑料支架的最佳管理方式。

方法

2007年4月至2017年9月期间,87例有症状的胆总管结石患者(中位年龄83.7岁)因难以完全内镜取石且全身状况不适合手术而接受7F塑料支架置入治疗。其中70例患者同意定期进行支架管理,每6个月(A组,n = 35)或每12个月(B组,n = 35)进行支架更换。其余17例患者未接受定期支架更换,临床症状出现时更换支架(C组)。我们评估了随访期间胆道并发症的发生率和支架通畅率。

结果

胆道塑料支架的通畅率在6个月时A组为91.4%,12个月时B组为88.6%。A组2.9%的患者发生急性胆管炎,B组8.6%的患者发生急性胆管炎。C组中,支架中位通畅时间为16.3个月,70.6%的病例因急性胆管炎或梗阻性黄疸进行了支架更换。虽然急性胆管炎发生率较高,但无胆道相关死亡病例。

结论

对于胆总管结石患者,每12个月进行一次塑料支架更换被认为是一种安全的操作。长期胆道支架置入会增加胆道并发症,但对于某些不适合进一步侵入性操作的特定患者而言,这可能是一个可接受的选择。

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