Saevels Kirsten, Robert Dominique, Van den Broeck Sylvie, Malfait Ronald, Gadisseur Alain, Jorens Philippe, Verlinden Anke
Department of Hematology Antwerp University Hospital Edegem Belgium.
Department of Intensive Care Medicine Antwerp University Hospital Edegem Belgium.
Clin Case Rep. 2017 Nov 29;6(1):115-118. doi: 10.1002/ccr3.1301. eCollection 2018 Jan.
The possibility of hemophagocytic lymphohistiocytosis should always be kept in mind when examining/treating a patient with fever of unknown origin and sepsis-like symptoms. Early diagnosis leading to prompt initiation of immunosuppressive therapy as well as aggressive supportive care, including correction of coagulation abnormalities and treatment of opportunistic infections, can decrease mortality.
在检查/治疗不明原因发热和脓毒症样症状的患者时,应始终考虑噬血细胞性淋巴组织细胞增生症的可能性。早期诊断并迅速开始免疫抑制治疗以及积极的支持治疗,包括纠正凝血异常和治疗机会性感染,可降低死亡率。