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桥本脑病——表现为持续性部分性癫痫发作及额叶病变。

Hashimoto's encephalopathy - presenting with epilepsia partialis continua and a frontal lobe lesion.

作者信息

Rukmangadachar Lokesh A, Dandapat Sudeepta, Bit-Ivan Esther N, Peng Yen-Yi

机构信息

Department of Neurology Southern Illinois University School of Medicine Springfield Illinois.

Department of Pathology Memorial Medical Center Springfield Illinois.

出版信息

Clin Case Rep. 2017 Dec 5;6(1):136-142. doi: 10.1002/ccr3.1306. eCollection 2018 Jan.

DOI:10.1002/ccr3.1306
PMID:29375853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5771906/
Abstract

We report a case of Hashimoto's encephalopathy (HE), who presented with epilepsia partialis continua (EPC) and a frontal lobe lesion. The diagnosis of HE remained elusive until the serum thyroid antibodies became positive 7 months after the onset of EPC. The histopathology of this frontal lesion showed nonvasculitic inflammation.

摘要

我们报告一例桥本脑病（HE），患者表现为持续性部分性癫痫（EPC）和额叶病变。直到EPC发作7个月后血清甲状腺抗体呈阳性，HE的诊断才得以明确。该额叶病变的组织病理学显示为非血管炎性炎症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/443d6fcf0389/CCR3-6-136-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/f75f73640a34/CCR3-6-136-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/b20c4823f98e/CCR3-6-136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/ad3efb7ce064/CCR3-6-136-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/03bbb60fa3e5/CCR3-6-136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/443d6fcf0389/CCR3-6-136-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/f75f73640a34/CCR3-6-136-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/b20c4823f98e/CCR3-6-136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/ad3efb7ce064/CCR3-6-136-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/03bbb60fa3e5/CCR3-6-136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb2a/5771906/443d6fcf0389/CCR3-6-136-g005.jpg

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JAMA Neurol. 2017 Apr 1;74(4):397-402. doi: 10.1001/jamaneurol.2016.5429.
2
Encephalopathy Associated with Autoimmune Thyroid Disease: A Potentially Reversible Condition.自身免疫性甲状腺疾病相关脑病：一种可能可逆的病症。
Case Rep Med. 2016;2016:9183979. doi: 10.1155/2016/9183979. Epub 2016 Apr 5.
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Hashimoto's encephalopathy: a report of three cases and relevant literature reviews.桥本脑病：三例报告及相关文献综述
Int J Clin Exp Med. 2015 Sep 15;8(9):16817-26. eCollection 2015.
4
Antithyroid Antibodies Are Implicated in Epileptogenesis of Adult Patients With Epilepsy.抗甲状腺抗体与成年癫痫患者的癫痫发生有关。
Medicine (Baltimore). 2015 Jul;94(26):e1059. doi: 10.1097/MD.0000000000001059.
5
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[Autoimmune encephalitis and its related-disorders].[自身免疫性脑炎及其相关疾病]
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