葡萄糖-6-磷酸脱氢酶缺乏症中的暴发性溶血
Fulminant hemolysis in glucose-6-phosphate dehydrogenase deficiency.
作者信息
Moiz Bushra, Ali Sidra Asad
机构信息
Section of Hematology and Transfusion Medicine Pathology and Laboratory Medicine The Aga Khan University Karachi Pakistan.
Junior Consultant Hematology Patel Hospital Karachi Pakistan.
出版信息
Clin Case Rep. 2017 Nov 24;6(1):224-225. doi: 10.1002/ccr3.1290. eCollection 2018 Jan.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder affecting some 400 million people worldwide. Though clinically silent, it may result in hemolysis on oxidative stress induced by drugs or infections. Viral hepatitis A with coexisting G6PD deficiency can be devastating associated with severe hemolysis, anemia, renal failure, and hepatic encephalopathy.
葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症是一种X连锁疾病，全球约有4亿人受其影响。尽管此种疾病临床上并无症状表现，但在药物或感染引发氧化应激时可能导致溶血。患有G6PD缺乏症的甲型病毒性肝炎可能会引发严重溶血、贫血、肾衰竭及肝性脑病，后果严重。
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