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急性甲型肝炎在未确诊的葡萄糖-6-磷酸脱氢酶缺乏患者中导致严重溶血和肾衰竭:一例报告及文献复习

Acute Hepatitis A Causing Severe Hemolysis and Renal Failure in Undiagnosed Glucose-6-Phosphate Dehydrogenase Deficient Patient: A Case Report and Review of the Literature.

作者信息

Abutineh Iman, Kreitman Kyle, Kothadia Jiten P, Ali Bilal, Jain Richa, Clark Ian, Maliakkal Benedict J, Nair Satheesh P

机构信息

Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

Methodist University Hospital, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, USA.

出版信息

Case Reports Hepatol. 2021 Jun 3;2021:5512883. doi: 10.1155/2021/5512883. eCollection 2021.

Abstract

Infection with hepatitis A virus is usually a self-limited illness that rarely results in fulminant liver failure. Severe hemolysis is an uncommon complication but has been reported in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Here, we report a case with undiagnosed G6PD deficiency who presented with hyperbilirubinemia, severe hemolysis, and acute renal failure precipitated by acute hepatitis A infection.

摘要

甲型肝炎病毒感染通常是一种自限性疾病,很少导致暴发性肝衰竭。严重溶血是一种罕见的并发症,但在葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症患者中已有报道。在此,我们报告一例未确诊G6PD缺乏症的病例,该患者因急性甲型肝炎感染出现高胆红素血症、严重溶血和急性肾衰竭。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825b/8192200/8e40e3620ade/CRIHEP2021-5512883.001.jpg

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