Devabhaktuni Subodh R, Chakfeh Eyas, Malik Ali O, Pengson Joshua A, Rana Jibran, Ahsan Chowdhury H
Division of Cardiology, University of Nevada School of Medicine, Las Vegas.
Department of Internal Medicine, University of Nevada School of Medicine, Las Vegas.
Clin Cardiol. 2018 Jan;41(1):131-136. doi: 10.1002/clc.22775. Epub 2018 Jan 29.
Subvalvular aortic stenosis (SAS) is one of the common adult congenital heart diseases, with a prevalence of 6.5%. It is usually diagnosed in the first decade of life. Echocardiography is the test of choice to diagnose SAS. Surgical correction is the best treatment modality, and the prognosis is usually excellent. In this review, we describe the pathophysiology, diagnosis, prognosis, and management of SAS with a focus on different pathophysiologic mechanisms, diagnostic approach, and prognosis of the disease by reviewing the current literature.
瓣下主动脉狭窄(SAS)是常见的成人先天性心脏病之一,患病率为6.5%。它通常在生命的第一个十年被诊断出来。超声心动图是诊断SAS的首选检查方法。手术矫正为最佳治疗方式,预后通常良好。在本综述中,我们通过回顾当前文献,描述了SAS的病理生理学、诊断、预后及管理,重点关注该疾病不同的病理生理机制、诊断方法及预后。