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人类输卵管和宫颈上皮中“基底”细胞和“储备”细胞的性质。

Nature of "basal" and "reserve" cells in oviductal and cervical epithelium in man.

作者信息

Peters W M

出版信息

J Clin Pathol. 1986 Mar;39(3):306-12. doi: 10.1136/jcp.39.3.306.

DOI:10.1136/jcp.39.3.306
PMID:2937810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC499768/
Abstract

The epithelium of the human fallopian tube (oviduct) and cervix were studied by histological, immunohistological, and ultrastructural methods with a view to establishing the nature of the so called "basal" and "reserve" cells. The results indicated that the "basal" cells of the oviductal epithelia were T lymphocytes, with a predominance of T cytotoxic and suppressor cells. A more heterogeneous inflammatory cell population was present in cervical epithelium, although once again T cytotoxic and suppressor cells were the most numerous subtype. The intraepithelial inflammatory cells were quite distinct from the cells commonly referred to as "reserve" cells (reserve cell hyperplasia), which have epithelial characteristics. The origin of the "reserve" cells is unclear, but they seem to arise within the epithelium. They probably represent an early sign of squamous metaplasia. The lymphoid tissue of fallopian tube and endocervix shows similarities with that of the endometrium and mucosal associated lymphoid tissue in general.

摘要

采用组织学、免疫组织学和超微结构方法对人输卵管(输卵管)和子宫颈上皮进行了研究,旨在确定所谓“基底”细胞和“储备”细胞的性质。结果表明,输卵管上皮的“基底”细胞是T淋巴细胞,以细胞毒性T细胞和抑制性T细胞为主。宫颈上皮中存在更具异质性的炎性细胞群体,尽管细胞毒性T细胞和抑制性T细胞再次成为数量最多的亚型。上皮内炎性细胞与通常称为“储备”细胞(储备细胞增生)的细胞截然不同,后者具有上皮特征。“储备”细胞的起源尚不清楚,但它们似乎起源于上皮内。它们可能代表鳞状化生的早期迹象。输卵管和子宫颈内膜的淋巴组织总体上与子宫内膜和黏膜相关淋巴组织相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/8312ca2088d6/jclinpath00198-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/46f86818186a/jclinpath00198-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/5f6a126a2014/jclinpath00198-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/1c58f7e1bfe4/jclinpath00198-0072-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/a77d84765bf5/jclinpath00198-0073-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/65404d4c104d/jclinpath00198-0073-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/5686dcbd2605/jclinpath00198-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/598a4f520532/jclinpath00198-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/8312ca2088d6/jclinpath00198-0075-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/46f86818186a/jclinpath00198-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/5f6a126a2014/jclinpath00198-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/1c58f7e1bfe4/jclinpath00198-0072-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/a77d84765bf5/jclinpath00198-0073-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/65404d4c104d/jclinpath00198-0073-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/5686dcbd2605/jclinpath00198-0074-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/598a4f520532/jclinpath00198-0074-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c6c/499768/8312ca2088d6/jclinpath00198-0075-a.jpg

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J Exp Med. 1982 Jun 1;155(6):1785-96. doi: 10.1084/jem.155.6.1785.
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Cells. 2024 Nov 28;13(23):1974. doi: 10.3390/cells13231974.
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Terminological discrepancies and novelties in the histological description of the female genital system: proposed amendments for clinical-translational anatomy.女性生殖系统组织学描述中的术语差异和新内容:临床转化解剖学的建议修正。
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Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq.使用 scRNA-seq 鉴定正常和输卵管积水疾病状态下人类输卵管的细胞异质性。
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