当我们测量细胞相关 HIV RNA 时，我们测量的是什么。
What do we measure when we measure cell-associated HIV RNA.
机构信息
Laboratory of Experimental Virology, Department of Medical Microbiology, Academic Medical Center of the University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands.
出版信息
Retrovirology. 2018 Jan 29;15(1):13. doi: 10.1186/s12977-018-0397-2.
Cell-associated (CA) HIV RNA has received much attention in recent years as a surrogate measure of the efficiency of HIV latency reversion and because it may provide an estimate of the viral reservoir size. This review provides an update on some recent insights in the biology and clinical utility of this biomarker. We discuss a number of important considerations to be taken into account when interpreting CA HIV RNA measurements, as well as different methods to measure this biomarker.
细胞相关（CA）HIV RNA 近年来受到了广泛关注，它可以作为 HIV 潜伏逆转效率的替代指标，并且可以估计病毒储存库的大小。本文综述了该生物标志物在生物学和临床应用方面的一些最新进展。我们讨论了在解释 CA HIV RNA 测量结果时需要考虑的一些重要因素，以及测量该生物标志物的不同方法。
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