Zaboski Brian A, Storch Eric A
School of Special Education, School Psychology & Early Childhood Studies, University of Florida, PO Box 117050, Norman Hall 1403, Gainesville, FL 32611, USA.
Menninger Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA.
Future Neurol. 2018 Feb;13(1):31-37. doi: 10.2217/fnl-2017-0030. Epub 2018 Jan 17.
Appearing in 40% of the cases of autism spectrum disorder (ASD), comorbid anxiety presents unique challenges for practitioners by amplifying problem behaviors such as social skills deficits, resistance to change and repetitive behaviors. Furthermore, comorbid ASD/anxiety strains familial relationships and increases parental stress. Research indicates that the neurobiological interactions between anxiety and ASD require comprehensive assessment approaches, modified cognitive behavioral therapy and carefully managed pharmacological interventions. Meta-analyses indicate that cognitive behavioral therapy with exposure is an effective treatment option when adequately accounting for social, familial and cognitive variables. The purpose of this focused review is to update readers on the latest research advances in comorbid ASD and anxiety, including prevalence, assessment, psychosocial and pharmacological treatment.
共病焦虑出现在40%的自闭症谱系障碍（ASD）病例中，它通过放大社交技能缺陷、抗拒改变和重复行为等问题行为，给从业者带来了独特的挑战。此外，ASD/焦虑共病会给家庭关系带来压力，并增加父母的压力。研究表明，焦虑与ASD之间的神经生物学相互作用需要综合评估方法、改良的认知行为疗法和精心管理的药物干预。荟萃分析表明，在充分考虑社会、家庭和认知变量的情况下，暴露认知行为疗法是一种有效的治疗选择。本重点综述的目的是向读者介绍ASD与焦虑共病的最新研究进展，包括患病率、评估、心理社会和药物治疗。
