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动态稳定化后小关节的变化:持续退变还是缓慢融合?

Changes of Facet Joints After Dynamic Stabilization: Continuous Degeneration or Slow Fusion?

作者信息

Yeh Mei-Yin, Kuo Chao-Hung, Wu Jau-Ching, Huang Wen-Cheng, Tu Tsung-Hsi, Fay Li-Yu, Wu Ching-Lan, Cheng Henrich

机构信息

Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.

Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Neurological Surgery, University of Washington, Seattle, Washington, USA.

出版信息

World Neurosurg. 2018 May;113:e45-e50. doi: 10.1016/j.wneu.2018.01.148. Epub 2018 Jan 31.

Abstract

BACKGROUND

The nonfusion pedicle-screw system Dynesys stabilization (DS) for lumbar degenerative disease aims to better preserve range of motion (ROM) than fixation and fusion systems. However, decreased ROM and unexpected facet fusion at the index level were observed after DS was applied with unknown etiology. The aim of this study is using radiologic parameters to explain the phenomenon of facet arthrodesis.

METHODS

The patients who underwent surgery for L4-5 spinal stenosis were sorted retrospectively into 2 groups: DS and microdiskectomy (MicD). Radiologic parameters including facet degeneration, evaluated by computed tomography or magnetic resonance image, and ROM, evaluated by dynamic radiographs, were compared perioperatively. A linear regression model was fitted to data points to calculate correlation over time. Postoperative facet arthrodesis at the index level was detected by computed tomography. Functional outcomes were also compared between groups.

RESULTS

A total of 61 patients (DS-to-MicD = 38:23) were followed 36.9 ± 16.8 months postoperatively. After surgery, both groups of patients had significant clinical improvement without difference between the 2 groups (all P > 0.05). In the DS group, significantly decreased ROM was observed after 24-month follow-up (P < 0.05). The correlation coefficient of facet degeneration over time and the facet fusion rate in the DS group were both significantly higher than in the MicD group (both P < 0.05).

CONCLUSIONS

The patients who underwent DS for L4-5 grade 1 spondylolisthesis experienced significantly reduced ROM and a positive correlation of facet degeneration over time postoperatively. The limited ROM at the index level could be a potential risk of facet degeneration and cause unexpected arthrodesis.

摘要

背景

用于腰椎退行性疾病的非融合椎弓根螺钉系统Dynesys稳定术(DS)旨在比固定和融合系统更好地保留活动度(ROM)。然而,应用DS后观察到活动度降低以及手术节段意外的小关节融合,其病因不明。本研究的目的是使用影像学参数来解释小关节融合的现象。

方法

对接受L4-5节段椎管狭窄手术的患者进行回顾性分组:DS组和显微椎间盘切除术(MicD)组。通过计算机断层扫描或磁共振成像评估的包括小关节退变在内的影像学参数,以及通过动态X线片评估的ROM,在围手术期进行比较。对数据点拟合线性回归模型以计算随时间的相关性。通过计算机断层扫描检测手术节段术后的小关节融合情况。还比较了两组之间的功能结果。

结果

共61例患者(DS组与MicD组 = 38:23)术后随访36.9 ± 16.8个月。术后,两组患者均有显著的临床改善,两组之间无差异(所有P > 0.05)。在DS组中,随访24个月后观察到活动度显著降低(P < 0.05)。DS组小关节退变随时间的相关系数和小关节融合率均显著高于MicD组(均P < 0.05)。

结论

接受DS治疗L4-5 Ⅰ度腰椎滑脱的患者术后活动度显著降低,且小关节退变随时间呈正相关。手术节段有限的活动度可能是小关节退变的潜在风险并导致意外的融合。

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