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腰椎滑脱症患者行Dynesys动态稳定术后的意外小关节融合

Unintended facet fusions after Dynesys dynamic stabilization in patients with spondylolisthesis.

作者信息

Fay Li-Yu, Huang Wen-Cheng, Chang Chih-Chang, Chang Hsuan-Kan, Tsai Tzu-Yun, Tu Tsung-Hsi, Wu Ching-Lan, Cheng Henrich, Wu Jau-Ching

机构信息

1Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.

2School of Medicine, National Yang-Ming University.

出版信息

J Neurosurg Spine. 2018 Dec 7;30(3):353-361. doi: 10.3171/2018.8.SPINE171328. Print 2019 Mar 1.

Abstract

OBJECTIVEThe pedicle screw-based Dynesys dynamic stabilization (DDS) has reportedly become a surgical option for lumbar spondylosis and spondylolisthesis. However, it is still unclear whether the dynamic construct remains mobile or eventually fuses. The aim of this study was to investigate the incidence of unintended facet arthrodesis after DDS and its association with spondylolisthesis.METHODSThis retrospective study was designed to review 105 consecutive patients with 1- or 2-level lumbar spondylosis who were treated with DDS surgery. The patients were then divided into 2 groups according to preexisting spondylolisthesis or not. All patients underwent laminectomies, foraminotomies, and DDS. The clinical outcomes were measured using visual analog scale (VAS) scores for back and leg pain, Japanese Orthopaedic Association (JOA) scores, and Oswestry Disability Index (ODI) scores. All medical records, including pre- and postoperative radiographs, CT scans, and MR images, were also reviewed and compared.RESULTSA total of 96 patients who completed the postoperative follow-up for more than 30 months were analyzed. The mean age was 64.1 ± 12.9 years, and the mean follow-up duration was 46.3 ± 12.0 months. There were 45 patients in the spondylolisthesis group and 51 patients in the nonspondylolisthesis group. The overall prevalence rate of unintended facet fusion was 52.1% in the series of DDS. Patients with spondylolisthesis were older (67.8 vs 60.8 years, p = 0.007) and had a higher incidence rate of facet arthrodesis (75.6% vs 31.4%, p < 0.001) than patients without spondylolisthesis. Patients who had spondylolisthesis or were older than 65 years were more likely to have facet arthrodesis (OR 6.76 and 4.82, respectively). There were no significant differences in clinical outcomes, including VAS back and leg pain, ODI, and JOA scores between the 2 groups. Furthermore, regardless of whether or not unintended facet arthrodesis occurred, all patients experienced significant improvement (all p < 0.05) in the clinical evaluations.CONCLUSIONSDuring the mean follow-up of almost 4 years, the prevalence of unintended facet arthrodesis was 52.1% in patients who underwent DDS. Although the clinical outcomes were not affected, elderly patients with spondylolisthesis might have a greater chance of facet fusion. This could be a cause of the limited range of motion at the index levels long after DDS.

摘要

目的

据报道,基于椎弓根螺钉的Dynesys动态稳定系统(DDS)已成为腰椎间盘退变和腰椎滑脱的一种手术选择。然而,目前尚不清楚这种动态结构是否仍保持活动状态或最终融合。本研究的目的是调查DDS术后意外小关节融合的发生率及其与腰椎滑脱的关系。

方法

本回顾性研究旨在回顾105例连续接受DDS手术治疗的1或2节段腰椎间盘退变患者。然后根据是否存在腰椎滑脱将患者分为2组。所有患者均接受了椎板切除术、椎间孔切开术和DDS手术。使用视觉模拟量表(VAS)评估腰腿痛情况、日本骨科协会(JOA)评分和Oswestry功能障碍指数(ODI)评分来衡量临床疗效。还对所有病历进行了回顾和比较,包括术前和术后的X线片、CT扫描和磁共振成像(MRI)。

结果

共分析了96例术后随访超过30个月的患者。平均年龄为64.1±12.9岁,平均随访时间为46.3±12.0个月。腰椎滑脱组45例,非腰椎滑脱组51例。在DDS系列中,意外小关节融合的总体发生率为52.1%。腰椎滑脱患者比无腰椎滑脱患者年龄更大(67.8岁对60.8岁,p = 0.007),小关节融合发生率更高(75.6%对31.4%,p < 0.001)。有腰椎滑脱或年龄大于65岁的患者更易发生小关节融合(分别为OR 6.76和4.82)。两组间临床疗效无显著差异,包括VAS腰腿痛评分、ODI评分和JOA评分。此外,无论是否发生意外小关节融合,所有患者在临床评估中均有显著改善(所有p < 0.05)。

结论

在平均近4年的随访中,接受DDS手术的患者意外小关节融合的发生率为52.1%。虽然临床疗效未受影响,但有腰椎滑脱的老年患者小关节融合的可能性可能更大。这可能是DDS术后很长时间手术节段活动范围受限的一个原因。

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